发明授权
US09034660B2 Detection of analytes via nanoparticle-labeled substances with electromagnetic read-write heads
有权
通过具有电磁读写头的纳米颗粒标记物质检测分析物
- 专利标题: Detection of analytes via nanoparticle-labeled substances with electromagnetic read-write heads
- 专利标题(中): 通过具有电磁读写头的纳米颗粒标记物质检测分析物
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申请号: US12888388申请日: 2010-09-22
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公开(公告)号: US09034660B2公开(公告)日: 2015-05-19
- 发明人: Dylan Joseph Boday , Lee Curtis Randall , Stephen Leonard Schwartz , Anna W. Topol , Daniel James Winarski
- 申请人: Dylan Joseph Boday , Lee Curtis Randall , Stephen Leonard Schwartz , Anna W. Topol , Daniel James Winarski
- 申请人地址: US NY Armonk
- 专利权人: International Business Machines Corporation
- 当前专利权人: International Business Machines Corporation
- 当前专利权人地址: US NY Armonk
- 代理机构: Cantor Colburn LLP
- 代理商 Bryan Butler
- 主分类号: G01N33/553
- IPC分类号: G01N33/553 ; G01N33/543 ; B82Y15/00
摘要:
A first set of antibodies are bonded to a substrate, and are exposed to and bonded with target antigens. A second set of antibodies are bonded to nanoparticles, and the nanoparticle labeled antibodies are exposed to the targeted antigens. An electromagnetic write-head magnetizes the nanoparticles, and then a read-sensor detects the freshly magnetized nanoparticles. The substrate comprises a flexible film or a Peltier material to allow selective heating and cooling of the antigens and antibodies. Nanoparticles of different magnetic properties may be selectively paired with antibodies associated with different antigens to allow different antigens to be detected upon a single scan by the read-sensor.
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