发明授权
- 专利标题: Signal-amplifying folded oligonucleotide
- 专利标题(中): 信号放大折叠寡核苷酸
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申请号: US13084148申请日: 2011-04-11
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公开(公告)号: US09139860B2公开(公告)日: 2015-09-22
- 发明人: Hong Gu Chun
- 申请人: Hong Gu Chun
- 申请人地址: KR Seoul
- 专利权人: Korea University Research and Business Foundation
- 当前专利权人: Korea University Research and Business Foundation
- 当前专利权人地址: KR Seoul
- 代理机构: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 代理商 Kongsik Kim; Elaine Morlock
- 主分类号: C07H21/00
- IPC分类号: C07H21/00 ; C07H21/04 ; C12Q1/00 ; C12Q1/68 ; C12Q1/70
摘要:
The present invention relates to a self-amplifying folded oligonucleotide structure for sensitive oligonucleotide sensing without polymerase chain reaction (PCR). A self-amplifying folded oligonucleotide structure comprise a target sensing sequence having stem loop structure, a signaling molecule and signal modifying molecule labeled two stems wherein the two stems include oligonucleotide sequence that is complementary to a target sensing sequence of another self-amplifying folded oligonucleotide structure.
公开/授权文献
- US20120259104A1 SELF-AMPLIFYING FOLDED OLIGONUCLEOTIDE STRUCTURE 公开/授权日:2012-10-11
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