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公开(公告)号：US20180238887A1
公开(公告)日：2018-08-23
申请号：US15307560
申请日：2015-04-27
发明人： Je Sang Ko , Hyoung-Tae An
IPC分类号： G01N33/574 , C12Q1/6886 , A61P35/00 , G01N33/50
CPC分类号： G01N33/57411 , A61K31/7088 , A61P35/00 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5011 , G01N2333/47
摘要： The present invention relates to a pharmaceutical use of actinin-4 involved in the induction of cervical cancer and more specifically, characterizes actinin-4 as a marker protein capable of inducing cervical cancer, thereby providing the pharmaceutical use of actinin-4 that can be used in the diagnosis, prevention or treatment of cervical cancer.
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公开(公告)号：US20180357419A1
公开(公告)日：2018-12-13
申请号：US15534708
申请日：2015-08-24
发明人： Kyung Ho Lee , Young In You , Seon Ju Kim , In Hyun Cho , Hyun Sik Yoon
IPC分类号： G06F21/57
CPC分类号： G06F21/577 , G06F21/57 , G06F2221/034
摘要： A method for measurement of an information-security-controlling status in accordance with the present disclosure includes receiving actual inspection data obtained by actually inspecting whether each domain complies with each security-controlling item, computing security-controlling status measurement scores for each domain on the basis of a significance grade of each control item, the degree of compliance with a corresponding control item, and a weighting set by a measurement manager, computing a final security-controlling status measurement score for a parent organization to which each domain belongs on the basis of an average of the security-controlling status measurement scores for each domain, and outputting the computed security-controlling status measurement scores and final security-controlling status measurement score.
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3.发明公开公开(公告)号：US20240212800A1
公开(公告)日：2024-06-27
申请号：US18544488
申请日：2023-12-19
申请人： LumanLab Inc. , Korea University Research and Business Foundation , Korea University Research and Business Foundation, Sejong Campus
发明人： Jae Hyun LIM , Chul Hyun CHO , Seung Pil PACK
CPC分类号： G16H10/20 , A61B5/16 , G16H50/20 , G16H50/30 , A61B2503/06
摘要： An electronic device and a method to assess a mental health state of an adolescent by using a survey formed based on an artificial intelligence (AI). The method comprises: collecting physical information of a user through a pre-installed application, verifying survey questions regarding a mental health depending on the physical information, and verifying answers to the verified survey questions through the application; forming additional survey questions after having verified the answers and calculating a prediction rate of an appearance of symptoms of a mental illness regarding the additional survey questions by using AI models; verifying a set of survey questions including a plurality of sub-questions depending on the calculated prediction rate; outputting the verified set of survey questions through the application; outputting result data by adjusting the prediction rate; and transmitting the outputted result data.
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公开(公告)号：US20220289657A1
公开(公告)日：2022-09-15
申请号：US17637565
申请日：2020-08-21
申请人： KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS , KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
发明人： Youngjoo BYUN , Hee Deung PARK , Sangjin NAM , Sang-Hyun SON , So Young HAM , Han Shin KIM
IPC分类号： C07C49/255 , C07C49/248 , C07C49/235 , A61K31/12 , A61P31/04
摘要： The present invention relates to a 4-gingerol derivative compound, or a racemate, isomer, or pharmaceutically acceptable salt thereof, the compound being capable of inhibiting biofilm formation and production of virulence factors. The 4-gingerol derivative compound according to the present invention has binding affinity to RhlR and corresponding RhlR antagonism activity that are significantly improved, and therefore can effectively inhibit biofilm formation and production of virulence factors. Furthermore, various bacterial infectious diseases caused by biofilms can be fundamentally prevented or treated by using a pharmaceutical composition comprising the 4-gingerol derivative compound, or a racemate, isomer, or pharmaceutically acceptable salt thereof as an active ingredient.
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公开(公告)号：US20200283364A1
公开(公告)日：2020-09-10
申请号：US16632592
申请日：2018-07-19
申请人： Korea University Research and Business Foundation, Sejong Campus , Korea University Research and Business Foundation
发明人： Youngjoo BYUN , Hee-Deung PARK , Sang-Hyun SON , Eunji CHA , So-Young HAM , Hyunsuk CHOI
IPC分类号： C07C49/255 , C07C49/245 , A61P31/04
摘要： The present invention relates to a gingerol derivative having inhibitory activity against biofilm formation and a pharmaceutical composition for preventing or treating infections caused by biofilms including the gingerol derivative as an active ingredient. The gingerol derivative of the present invention exhibits significantly improved binding affinity for LasR and inhibitory activity against biofilm formation. Therefore, the gingerol derivative of the present invention can act on various membrane surfaces where biofilms tend to form and can effectively inhibit the formation of the corresponding biofilms. In addition, the use of the pharmaceutical composition according to the present invention can fundamentally prevent or treat a variety of infections caused by biofilms due to the presence of the gingerol derivative in the pharmaceutical composition.
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公开(公告)号：US11964935B2
公开(公告)日：2024-04-23
申请号：US16632592
申请日：2018-07-19
申请人： Korea University Research and Business Foundation, Sejong Campus , Korea University Research and Business Foundation
发明人： Youngjoo Byun , Hee-Deung Park , Sang-Hyun Son , Eunji Cha , So-Young Ham , Hyunsuk Choi
IPC分类号： C07C49/255 , A61P31/04 , C07C49/245
CPC分类号： C07C49/255 , A61P31/04 , C07C49/245
摘要： The present invention relates to a gingerol derivative having inhibitory activity against biofilm formation and a pharmaceutical composition for preventing or treating infections caused by biofilms including the gingerol derivative as an active ingredient. The gingerol derivative of the present invention exhibits significantly improved binding affinity for LasR and inhibitory activity against biofilm formation. Therefore, the gingerol derivative of the present invention can act on various membrane surfaces where biofilms tend to form and can effectively inhibit the formation of the corresponding biofilms. In addition, the use of the pharmaceutical composition according to the present invention can fundamentally prevent or treat a variety of infections caused by biofilms due to the presence of the gingerol derivative in the pharmaceutical composition.
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公开(公告)号：US11298534B2
公开(公告)日：2022-04-12
申请号：US16235498
申请日：2018-12-28
申请人： KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION , Korea University Research and Business Foundation, Sejong Campus
发明人： Hoon Jai Chun , Jung Hwa Hong , Dong Geun Sul , Bora Keum , Eun Sun Kim , Hyuk Soon Choi , Seung Han Kim
摘要： A stimulator for a digestive organ includes a case, a substrate member disposed in the case, and an electrode member connected to the substrate member and extending to protrude outwardly from the case. The electrode member may have a shape of a wire and may be configured to provide an electrical stimulation in a state of being inserted and fixed at a predetermined location within a digestive organ.
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公开(公告)号：US20190321631A1
公开(公告)日：2019-10-24
申请号：US16235498
申请日：2018-12-28
申请人： KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION , KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
发明人： Hoon Jai Chun , Jung Hwa Hong , Dong Geun Sul , Bora Keum , Eun Sun Kim , Hyuk Soon Choi , Seung Han Kim
摘要： A stimulator for a digestive organ includes a case, a substrate member disposed in the case, and an electrode member connected to the substrate member and extending to protrude outwardly from the case. The electrode member may have a shape of a wire and may be configured to provide an electrical stimulation in a state of being inserted and fixed at a predetermined location within a digestive organ.
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公开(公告)号：US12124578B2
公开(公告)日：2024-10-22
申请号：US18215678
申请日：2023-06-28
发明人： Dong Hoon Lee , Wonsuk Choi , Kyungho Joo , Seyoung Lee , Aram Cho
CPC分类号： G06F21/566 , H04L12/40013 , G06F2221/034 , H04L2012/40215 , H04L2012/40273
摘要： A system and method for identifying a compromised controller using an intentional error are provided. The method, performed by an electronic device in a controller area network (CAN), for identifying a compromised electronic control unit (ECU) that transmits an attack message on a CAN bus in a periodic transmission cycle. The method includes, in response to detecting the attack message, transitioning a first ECU among a plurality of ECUs connected to the CAN bus to a bus-off state intentionally, and determining whether the first ECU is the compromised ECU based at least in part on a time, which is predicted from recovery parameters related to the first ECU, for when the first ECU resumes transmission of a CAN message and a time when the attack message is redetected on the CAN bus.
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公开(公告)号：US20240349601A1
公开(公告)日：2024-10-17
申请号：US18614333
申请日：2024-03-22
发明人： Daeho Lee , Han Young Woo , Hwasook Ryu , Seokgyu Yoon , Hyejin Jung , Chaeyeon Park , Venkata Suman Krishna Jonnadula , Min Hun Jee
IPC分类号： H10K85/60 , C07D495/04 , C07D495/14 , H10K30/40
CPC分类号： H10K85/657 , C07D495/04 , C07D495/14 , H10K85/6576 , H10K30/40
摘要： A condensed cyclic compound represented by Formula 1, an organic photodetector including the condensed cyclic compound. and an electronic apparatus including the organic photodetector are provided:
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