Invention Grant
US09233957B2 5-carbamoyl-adamantan-2-yl amide derivatives, pharmaceutically acceptable salts thereof and preparation process thereof
有权
5-氨基甲酰基 - 金刚烷-2-基酰胺衍生物及其药学上可接受的盐及其制备方法
- Patent Title: 5-carbamoyl-adamantan-2-yl amide derivatives, pharmaceutically acceptable salts thereof and preparation process thereof
- Patent Title (中): 5-氨基甲酰基 - 金刚烷-2-基酰胺衍生物及其药学上可接受的盐及其制备方法
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Application No.: US14123043Application Date: 2012-06-11
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Publication No.: US09233957B2Publication Date: 2016-01-12
- Inventor: Coo-Min Chung , Choon-Ho Ryu , Yoon-Kyeong Lee , Jin-Sook Moon , Hye-Sung Lee , Seon-Jeong Lee , Kyung-Seok Oh
- Applicant: Coo-Min Chung , Choon-Ho Ryu , Yoon-Kyeong Lee , Jin-Sook Moon , Hye-Sung Lee , Seon-Jeong Lee , Kyung-Seok Oh
- Applicant Address: KR Seoul
- Assignee: SK BIOPHARMACEUTICALS CO., LTD.
- Current Assignee: SK BIOPHARMACEUTICALS CO., LTD.
- Current Assignee Address: KR Seoul
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: KR10-2011-0056060 20110610; KR10-2012-0062049 20120611
- International Application: PCT/KR2012/004602 WO 20120611
- International Announcement: WO2012/169863 WO 20121213
- Main IPC: C07D207/34
- IPC: C07D207/34 ; C07D213/81 ; C07D213/89 ; C07D215/48 ; C07D215/60 ; C07D417/04 ; C07D333/38 ; C07D261/10 ; C07D307/56 ; C07D261/18 ; C07D307/68 ; C07D401/04 ; C07D413/04 ; C07D413/12
Abstract:
Provided are a novel derivative of 5-carbamoyl adamantan-2-yl amide of Formula (I), or a pharmaceutically acceptable salt thereof, and a pharmaceutical use thereof for inhibiting the activity of 11β-hydroxystreroid dehydrogenase type 1 (11b-HSD1) or for preventing and/or treating various diseases mediated by 11β-hydroxystreroid dehydrogenase type 1.
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