发明授权
- 专利标题： Fed-batch methods for producing adalimumab
- 专利标题（中）： 用于生产阿达木单抗的联合分批方法
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申请号： US14157460申请日： 2014-01-16
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公开(公告)号： US09234032B2公开(公告)日： 2016-01-12
- 发明人: Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-hsiang D. Chang , Thomas Seewoester
- 申请人： AbbVie Inc.
- 申请人地址： US IL North Chicago
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： US IL North Chicago
- 代理机构： Foley Hoag LLP
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; C07K16/00 ; C07K16/28 ; C12N5/00 ; C12N5/073
摘要：
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
公开/授权文献
- US20140134675A1 CELL CULTURE IMPROVEMENTS 公开/授权日：2014-05-15
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