发明授权
US09238688B2 Retinol-modified collagen, method for producing same, and external composition for skin containing same
有权
视黄醇改性胶原蛋白，其制备方法和含有其的皮肤外用组合物
- 专利标题： Retinol-modified collagen, method for producing same, and external composition for skin containing same
- 专利标题（中）： 视黄醇改性胶原蛋白，其制备方法和含有其的皮肤外用组合物
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申请号： US13703477申请日： 2011-06-15
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公开(公告)号： US09238688B2公开(公告)日： 2016-01-19
- 发明人: Masao Tanihara , Kana Takaichi , Mariko Maeda , Tsukasa Mitsui , Kazushi Yamamoto , Akiko Hirano
- 申请人： Masao Tanihara , Kana Takaichi , Mariko Maeda , Tsukasa Mitsui , Kazushi Yamamoto , Akiko Hirano
- 申请人地址： JP Nara JP Osaka
- 专利权人： NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY,SUNSTAR INC.
- 当前专利权人： NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY,SUNSTAR INC.
- 当前专利权人地址： JP Nara JP Osaka
- 代理机构： Wenderoth, Lind & Ponack, L.L.P.
- 优先权： JP2010-136293 20100615
- 国际申请： PCT/JP2011/063704 WO 20110615
- 国际公布： WO2011/158864 WO 20111222
- 主分类号： C07K14/78
- IPC分类号： C07K14/78 ; A61Q19/08 ; A61Q19/00 ; C07K1/107 ; A61K8/67 ; A61K31/07 ; A61K38/39 ; A61Q1/00 ; A61Q1/02 ; A61Q1/12 ; A61Q5/02 ; A61Q5/12 ; A61Q19/10
摘要：
Disclosed is a compound which exhibits a higher effect of preventing wrinkle formation, a higher effect of improving wrinkles, a higher effect of making the skin beautiful, and a higher effect of improving skin quality than conventional retinol and retinol derivatives in a sustained manner. Further disclosed are a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient. More specifically disclosed are retinol-modified collagen in which a dicarboxylic acid is attached to at least one hydroxyl group of collagen and retinol is attached to a carboxyl group of at least one attached dicarboxylic acid, a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.
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