- 专利标题: Ketol-acid reductoisomerase using NADH
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申请号: US13838869申请日: 2013-03-15
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公开(公告)号: US09238801B2公开(公告)日: 2016-01-19
- 发明人: Yougen Li , Der-Ing Liao , Mark J. Nelson , Daniel P. Okeefe
- 申请人: BUTAMAX(TM) ADVANCED BIOFUELS LLC
- 申请人地址: US DE Wilmington
- 专利权人: Butamax Advanced Biofuels LLC
- 当前专利权人: Butamax Advanced Biofuels LLC
- 当前专利权人地址: US DE Wilmington
- 主分类号: C12N9/02
- IPC分类号: C12N9/02 ; C12N15/00 ; C12P21/06 ; C12P21/04 ; C07H21/04 ; C12N9/04 ; C12N15/70 ; C12N15/10 ; C12Q1/26 ; C12P7/16 ; C12N15/81 ; C12P7/42
摘要:
Methods for the evolution of NADPH specific ketol-acid reductoisomerase enzymes to acquire NADH specificity are provided. Specific mutant ketol-acid reductoisomerase enzymes isolated from Pseudomonas that have undergone co-factor switching to utilize NADH are described.
公开/授权文献
- US20140057329A1 KETOL-ACID REDUCTOISOMERASE USING NADH 公开/授权日:2014-02-27
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