Invention Grant
- Patent Title: Substituted pyrazines as cadherin-11 inhibitors
- Patent Title (中): 取代的吡嗪作为钙粘蛋白-11抑制剂
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Application No.: US14323374Application Date: 2014-07-03
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Publication No.: US09284368B2Publication Date: 2016-03-15
- Inventor: Stephen W. Byers , Sivanesan Dakshanamurthy , Jaime M. Guidry Auvil , Milton L. Brown
- Applicant: Georgetown University
- Applicant Address: US DC Washington
- Assignee: GEORGETOWN UNIVERSITY
- Current Assignee: GEORGETOWN UNIVERSITY
- Current Assignee Address: US DC Washington
- Agency: Kilpatrick Townsend & Stockton, LLP
- Main IPC: C07D241/12
- IPC: C07D241/12 ; C07K16/18 ; C07D213/30 ; C07D241/42 ; A61K31/343 ; A61K31/44 ; A61K31/473 ; A61K31/498 ; A61K45/06 ; C07D215/14 ; C07D307/77
Abstract:
This invention provides for a method of preventing or treating a cadherin-11 related disease in a subject, which includes administering to the subject an effective amount of a compound of the following formula: or a pharmaceutically acceptable salt or prodrug thereof, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, X1 and X2 are as defined herein.
Public/Granted literature
- US20150064168A1 Cadherin-11 Inhibitors and Methods of Use Thereof Public/Granted day:2015-03-05
Information query
