发明授权
- 专利标题： Method of stimulating an immune response using a pseudotyped lentivirus
- 专利标题（中）： 使用假型慢病毒刺激免疫应答的方法
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申请号： US14532371申请日： 2014-11-04
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公开(公告)号： US09303072B2公开(公告)日： 2016-04-05
- 发明人: Pin Wang , Lili Yang , David Baltimore
- 申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY
- 申请人地址： US CA Pasadena
- 专利权人： CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人： CALIFORNIA INSTITUTE OF TECHNOLOGY
- 当前专利权人地址： US CA Pasadena
- 代理机构： Marshall, Gerstein & Borun LLP
- 主分类号： A01N63/00
- IPC分类号： A01N63/00 ; C07K14/005 ; A61K31/70 ; A61K38/17 ; A61K38/19 ; A61K38/20 ; A61K35/76 ; C12N15/86 ; A61K39/21 ; C12N7/00 ; A61K39/00
摘要：
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.
公开/授权文献
- US20150175667A1 TARGETED GENE DELIVERY FOR DENDRITIC CELL VACCINATION 公开/授权日：2015-06-25
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