Invention Grant
- Patent Title: Vaccines directed to langerhans cells
- Patent Title (中): 疫苗针对朗格汉斯细胞
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Application No.: US13863131Application Date: 2013-04-15
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Publication No.: US09315580B2Publication Date: 2016-04-19
- Inventor: Jacques F. Banchereau , Gerard Zurawski , Sandra Zurawski , Eynav Klechevsky , SangKon Oh
- Applicant: Baylor Research Institute
- Applicant Address: US TX Dallas
- Assignee: Baylor Research Institute
- Current Assignee: Baylor Research Institute
- Current Assignee Address: US TX Dallas
- Agency: Norton Rose Fulbright US LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; C07K16/28 ; A61K39/00 ; A61K39/145 ; A61K39/21 ; C07K14/47 ; C12N7/00 ; C07K14/005 ; A61K39/12
Abstract:
The present invention includes isolated anti-Langerin vaccines, methods for making and using an isolated anti-Langerin antibody or binding fragment thereof and one or more antigenic peptides at the carboxy-terminus of the isolated anti-Langerin antibody, wherein when two or more antigenic peptides are present, the peptides are separated by the one or more linker peptides that comprise at least one glycosylation site. The present invention also includes isolated vectors for the expression of the anti-Langerin antigen delivery vectors and their manufactures and use.
Public/Granted literature
- US20140030264A1 VACCINES DIRECTED TO LANGERHANS CELLS Public/Granted day:2014-01-30
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