发明授权
- 专利标题： Protective effects and application of a lactobacillus plantarum on the alleviation of lead toxicity
- 专利标题（中）： 植物乳杆菌的保护作用和应用对铅毒性的缓解
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申请号： US14118867申请日： 2012-07-18
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公开(公告)号： US09320766B2公开(公告)日： 2016-04-26
- 发明人: Fengwei Tian , Wei Chen , Qixiao Zhai , Hao Zhang , Jianxin Zhao , Gang Wang , Yuanda Song , Qiuxiang Zhang , Xiaoming Liu , Min Guo , Daming Fan
- 申请人： Fengwei Tian , Wei Chen , Qixiao Zhai , Hao Zhang , Jianxin Zhao , Gang Wang , Yuanda Song , Qiuxiang Zhang , Xiaoming Liu , Min Guo , Daming Fan
- 申请人地址： CN Wuxi
- 专利权人： Jiangnan University
- 当前专利权人： Jiangnan University
- 当前专利权人地址： CN Wuxi
- 代理机构： CBM Patent Consulting, LLC
- 优先权： CN201210046323 20120228
- 国际申请： PCT/CN2012/078799 WO 20120718
- 国际公布： WO2013/127146 WO 20130906
- 主分类号： A61K35/747
- IPC分类号： A61K35/747 ; C12R1/25 ; A23L1/30 ; A23C13/16 ; A23C19/032 ; A23C9/123 ; A23C11/10 ; C12N1/20 ; A23L2/38 ; A23L1/212
摘要：
The Lactobacillus plantarum CCFM8661 is tolerant to acid and lead ions in vitro which can tolerate lead ions solution with the initial concentration of 150 mg/L, and has a strong capability of binding lead ions, which can reduce the lead level in mice blood, liver, kidney and stomach, significantly improve antioxidant indicators and alleviate pathological symptoms of lead exposed mice.
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