A preamble, a plurality of data segments of a data payload of a single data unit, and one or more midambles, each included between respective data segments, are generated. Data to be included in the data segments is processed, including at least one of: encoding all data payload bits of all segments as a whole, encoding data payload bits on a per segment basis, scrambling all data payload bits of all segments as a whole, scrambling data payload bits on a per segment basis, adding padding bits to only a last data segment, or adding padding bits to each data segment separately. The single data unit, including the preamble, the plurality of data segments and the one or more midambles, is caused to be transmitted. A network interface of a communication device may perform the generation and the data processing, and may cause the transmission of the single data unit.