Invention Grant
- Patent Title: Method for purification of cleaved pro-insulin
- Patent Title (中): 纯化前胰岛素的方法
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Application No.: US14348634Application Date: 2012-09-28
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Publication No.: US09409967B2Publication Date: 2016-08-09
- Inventor: Eggert Brekkan , Kjell Eriksson , Bo-Lennart Johansson , Jamil Shanagar
- Applicant: GE HEALTHCARE BIO-SCIENCES AB
- Applicant Address: SE Uppsala
- Assignee: GE Healthcare BioProcess R&D AB
- Current Assignee: GE Healthcare BioProcess R&D AB
- Current Assignee Address: SE Uppsala
- Agency: Wood IP LLC
- Priority: SE1100722 20110930
- International Application: PCT/SE2012/051040 WO 20120928
- International Announcement: WO2013/048330 WO 20130404
- Main IPC: C07K1/18
- IPC: C07K1/18 ; A61K38/28 ; B01D15/08 ; B01D15/26 ; B01D15/36 ; B01J20/285 ; B01J20/286 ; B01J20/32 ; C07K14/62 ; B01J39/26 ; B01J20/288
Abstract:
The present invention is within the field of biomolecule purification. More closely the invention relates to chromatographic purification of insulin using a specific kind of shell beads having an inner core and an outer functionalized layer. The method enables purification at high flow rates and high purity, over 90%.
Public/Granted literature
- US20140243498A1 METHOD FOR PURIFICATION OF CLEAVED PRO-INSULIN Public/Granted day:2014-08-28
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