Invention Grant
- Patent Title: Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein
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Application No.: US14560263Application Date: 2014-12-04
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Publication No.: US09447404B2Publication Date: 2016-09-20
- Inventor: Michael Breuer , Bernhard Hauer , Dieter Jendrossek , Gabrielle Siedenburg , Juergen Pleiss , Demet Sirim , Silvia Fadenrecht
- Applicant: BASF SE
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agency: Drinker Biddle & Reath LLP
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12N1/19 ; C12P5/02 ; C12N9/90 ; C12N9/88 ; C12P7/02 ; C12P5/00

Abstract:
The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.
Public/Granted literature
- US20150104851A1 METHOD FOR THE BIOCATALYTIC CYCLIZATION OF TERPENES AND CYCLASE MUTANTS EMPLOYABLE THEREIN Public/Granted day:2015-04-16
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