Invention Grant
- Patent Title: Method for generating non-pluripotent progenitors of surrogate pancreatic cells
- Patent Title (中): 产生替代胰腺细胞的非多能祖细胞的方法
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Application No.: US14693245Application Date: 2015-04-22
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Publication No.: US09474772B2Publication Date: 2016-10-25
- Inventor: William L. Rust
- Applicant: Seraxis, Inc.
- Applicant Address: US MD Germantown
- Assignee: Seraxis, Inc.
- Current Assignee: Seraxis, Inc.
- Current Assignee Address: US MD Germantown
- Agency: Foley & Lardner LLP
- Main IPC: C12N5/00
- IPC: C12N5/00 ; A61K35/39 ; C12N5/071
Abstract:
Fresh human pancreas tissue can be used as a source of cells whence to identify and select a non-stem cell population that is predisposed to be a source for surrogate pancreatic cells that can be used in treating insulin-dependent diabetes. The progenitors of these surrogate pancreatic cells have no reprogramming genes integrated into their genomes, differentiate to the pancreatic lineage pursuant to a protocol that employs only defined reagents, and are substantially unable to differentiate to the mesodermal lineage.
Public/Granted literature
- US20150231181A1 STEM CELLS AND PANCREATIC CELLS USEFUL FOR THE TREATMENT OF INSULIN-DEPENDENT DIABETES MELLITUS Public/Granted day:2015-08-20
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