- 专利标题： Modulation of chemosensory receptors and ligands associated therewith
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申请号： US11760592申请日： 2007-06-08
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公开(公告)号： US09603848B2公开(公告)日： 2017-03-28
- 发明人: Guy Servant , Xiaodong Li , Feng Zhang , Haitian Liu , Catherine Tachdjian , Xiao-Qing Tang , Sara Werner , Marketa Rinnova , Qing Chen , Albert Zlotnik , Mark Zoller , Boris Klebansky , Richard Fine , Xinshan Kang
- 申请人： Guy Servant , Xiaodong Li , Feng Zhang , Haitian Liu , Catherine Tachdjian , Xiao-Qing Tang , Sara Werner , Marketa Rinnova , Qing Chen , Albert Zlotnik , Mark Zoller , Boris Klebansky , Richard Fine , Xinshan Kang
- 申请人地址： US CA San Diego
- 专利权人： Senomyx, Inc.
- 当前专利权人： Senomyx, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Knobbe Martens Olson & Bear LLP
- 主分类号： A61K31/495
- IPC分类号： A61K31/495 ; A61K31/517 ; A61K31/519 ; C07D239/80 ; C07D239/95 ; C07D239/96 ; C07D285/15 ; C07D487/04 ; C07D491/04 ; G01N33/74 ; G06F19/16 ; G06F19/18
摘要：
The present invention provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors as well as modifiers capable of modulating chemosensory receptors and their ligands.