- 专利标题: Indole and indoline derivatives and methods of use thereof
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申请号: US12727723申请日: 2010-03-19
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公开(公告)号: US09625475B2公开(公告)日: 2017-04-18
- 发明人: Michael R. Schrimpf , Chih-Hung Lee , Tao Li , Gregory A. Gfesser , Kathleen H. Mortell , Ramin Faghih , Diana L. Nersesian , Kevin B. Sippy , William H. Bunnelle , Marc Scanio , Lei Shi , Murali Gopalakrishnan , Diana L. Donnelly-Roberts , Min Hu
- 申请人: Michael R. Schrimpf , Chih-Hung Lee , Tao Li , Gregory A. Gfesser , Kathleen H. Mortell , Ramin Faghih , Diana L. Nersesian , Kevin B. Sippy , William H. Bunnelle , Marc Scanio , Lei Shi , Murali Gopalakrishnan , Diana L. Donnelly-Roberts , Min Hu
- 申请人地址: US IL North Chicago
- 专利权人: AbbVie Inc.
- 当前专利权人: AbbVie Inc.
- 当前专利权人地址: US IL North Chicago
- 代理商 Portia Chen
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; C07D487/00 ; C07D491/00 ; C07D498/00 ; C07D513/00 ; C07D515/00 ; G01N33/68 ; C07D471/18 ; C07D487/10 ; G01N33/50
摘要:
The present application relates to indole and indoline derivatives of formula (I), (II), (III), (IV), (V), or (VI) wherein a, R1, R2, R3, R4, R5, U, V, W, X, Y, and Z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.
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