Invention Grant
- Patent Title: Capture purification processes for proteins expressed in a non-mammalian system
-
Application No.: US14599336Application Date: 2015-01-16
-
Publication No.: US09643997B2Publication Date: 2017-05-09
- Inventor: Joseph Edward Shultz , Roger Hart
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Raymond M. Doss
- Main IPC: C07K1/14
- IPC: C07K1/14 ; C07K1/22 ; C07K1/18 ; C07K1/32 ; C07K16/00
Abstract:
Methods of purifying proteins expressed in non-mammalian expression systems in a non-native soluble form directly from cell lysate are disclosed. Methods of purifying proteins expressed in non-mammalian expression systems in a non-native limited solubility form directly from a refold solution are also disclosed. Resin regeneration methods are also provided.
Public/Granted literature
- US20150361130A1 Capture Purification Processes for Proteins Expressed in a Non-Mammalian System Public/Granted day:2015-12-17
Information query
