- Patent Title: Intermediates for preparing triazole agonists of the APJ receptor
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Application No.: US15298686Application Date: 2016-10-20
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Publication No.: US09656998B2Publication Date: 2017-05-23
- Inventor: Ning Chen , Xiaoqi Chen , Richard V. Connors , Jeffrey Deignan , Paul John Dransfield , Xiaohui Du , Zice Fu , Julie Anne Heath , Daniel B. Horne , Jonathan Houze , Matthew R. Kaller , David John Kopecky , Su-Jen Lai , Zhihua Ma , Lawrence R. McGee , Julio C. Medina , Jeffrey T. Mihalic , Nobuko Nishimura , Steven H. Olson , Vatee Pattaropong , Xiaodong Wang , Kevin Yang , Mikkel V. Debenedetto , Robert P. Farrell , Simon J. Hedley , Ted C. Judd
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard P. Friedrichsen
- Main IPC: C07D213/82
- IPC: C07D213/82 ; C07D241/24 ; C07D401/12 ; C07D401/14 ; C07D401/04 ; C07D413/04 ; A61K31/4439 ; A61K31/444 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/513 ; A61K45/06 ; C07B57/00 ; C07B59/00 ; C07D211/54 ; C07D213/71 ; C07D239/26 ; C07D239/30 ; C07D241/12 ; C07D249/08 ; C07D405/14 ; C07D413/14 ; C07D417/14 ; C07D471/04 ; A61K31/695
Abstract:
Compounds of Formula V, salts thereof, tautomers thereof, and salts of the tautomers are useful intermediates in the synthesis of agonists of the APJ Receptor. Compounds of Formula V have the following structure: where the definitions of the variables are provided herein.
Public/Granted literature
- US20170042897A1 TRIAZOLE AGONISTS OF THE APJ RECEPTOR Public/Granted day:2017-02-16
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