- 专利标题: Vectors and methods to treat ischemia
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申请号: US14776673申请日: 2014-03-14
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公开(公告)号: US09663564B2公开(公告)日: 2017-05-30
- 发明人: Jan Nolta , Karen Pepper , Fernando Fierro , Gerhard Bauer
- 申请人: The Regents of the University of California , Jan Nolta , Karen Pepper , Fernando Fierro , Gerhard Bauer
- 申请人地址: US CA Oakland
- 专利权人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 当前专利权人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 当前专利权人地址: US CA Oakland
- 代理机构: Foley & Lardner LLP
- 代理商 Antoinette F. Konski
- 优先权: WOPCT/US2013/057721 20130830
- 国际申请: PCT/US2014/029386 WO 20140314
- 国际公布: WO2014/144815 WO 20140918
- 主分类号: C12N15/00
- IPC分类号: C12N15/00 ; A01N63/00 ; A61K48/00 ; C07K14/475 ; C12N7/00 ; C12N15/86 ; A61K38/00
摘要:
This disclosure relates to vectors, isolated cells, compositions, and methods for the treatment of critical limb ischemia and associated disorders. One aspect of the disclosure relates to a vector comprising a nucleic acid encoding a 165A isoform VEGF protein and a promoter that regulates expression of the nucleic acid encoding the VEGF.
公开/授权文献
- US20160046685A1 VECTORS AND METHODS TO TREAT ISCHEMIA 公开/授权日:2016-02-18
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