A method for manufacturing on a compound glass substrate a multi-colored LED for use in a video display board includes preparing a first masking layer on a compound glass substrate; depositing a first-color epitaxial layer on the first-color LED growing region and the first masking layer, to form a first-color LED; removing the first masking layer and the first-color epitaxial layer on the first masking layer; preparing a second masking layer, wherein the second masking layer is used to mask another region except a second-color LED growing region; depositing a second-color epitaxial layer on the second-color LED growing region and the second masking layer, to form a second-color LED; removing the second masking layer and the second-color epitaxial layer on the second masking layer; and grinding, cleaning, and performing an electrical test on a surface of the compound glass substrate.