OBTAINING DATA FOR AUTOMATIC GLAUCOMA SCREENING, AND SCREENING AND DIAGNOSTIC TECHNIQUES AND SYSTEMS USING THE DATA
    1.
    发明申请
    OBTAINING DATA FOR AUTOMATIC GLAUCOMA SCREENING, AND SCREENING AND DIAGNOSTIC TECHNIQUES AND SYSTEMS USING THE DATA 有权
    获取用于自动GLAUCOMA筛选的数据,以及使用数据的筛选和诊断技术和系统

    公开(公告)号:US20160100753A1

    公开(公告)日:2016-04-14

    申请号:US14828262

    申请日:2015-08-17

    摘要: A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode. Texture analysis is performed on the fundus images to classify them based on their quality, and only images which are determined to meet a quality criterion are subjected to an analysis to determine if they exhibit glaucoma indicators. Also, the images are put into a standard format. The system may include estimating the position of the optic cup by combining results from multiple optic cup segmentation techniques. The system may include estimating the position of the optic disc by applying edge detection to the funds image, excluding edge points that are unlikely to be optic disc boundary points, and estimating the position of an optic disc by fitting an ellipse to the remaining edge points.

    摘要翻译: 使用非立体眼底图像来获得多个青光眼指示符。 此外,用于受试者的基因组数据用于获得与与青光眼相关的一个或多个基因和/或SNP相关的遗传标记数据。 青光眼指标和遗传标记数据被输入到适应模型中,该模型用于产生指示受试者青光眼风险的输出。 综合来看,遗传指标和基因组数据对于青光眼的风险比孤立的两者之一更有信息。 自适应模型可以是两阶段模型,其具有第一阶段,其中通过第一自适应模型模块将个体遗传指标与基因组数据的相应部分组合以形成相应的第一输出,第二阶段中,第一输出是 通过第二自适应模式组合。 对眼底图像进行纹理分析,根据其质量对其进行分类,仅对满足质量标准的图像进行分析,以确定其是否呈现青光眼指标。 此外,图像被放入标准格式。 该系统可以包括通过组合来自多个光学杯分割技术的结果来估计光学杯的位置。 该系统可以包括通过对资金图像应用边缘检测来估计视盘的位置,不包括不太可能是视盘边界点的边缘点,以及通过将椭圆拟合到剩余边缘点来估计视盘的位置 。

    Obtaining data for automatic glaucoma screening, and screening and diagnostic techniques and systems using the data
    2.
    发明授权
    Obtaining data for automatic glaucoma screening, and screening and diagnostic techniques and systems using the data 有权
    获取自动青光眼筛查数据,以及使用数据的筛选和诊断技术和系统

    公开(公告)号:US09107617B2

    公开(公告)日:2015-08-18

    申请号:US13510290

    申请日:2010-11-16

    IPC分类号: A61B3/12 A61B5/02 A61B5/00

    摘要: A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode. Texture analysis is performed on the fundus images to classify them based on their quality, and only images which are determined to meet a quality criterion are subjected to an analysis to determine if they exhibit glaucoma indicators. Also, the images are put into a standard format. The system may include estimating the position of the optic cup by combining results from multiple optic cup segmentation techniques. The system may include estimating the position of the optic disc by applying edge detection to the funds image, excluding edge points that are unlikely to be optic disc boundary points, and estimating the position of an optic disc by fitting an ellipse to the remaining edge points.

    摘要翻译: 使用非立体眼底图像来获得多个青光眼指示符。 此外,用于受试者的基因组数据用于获得与与青光眼相关的一个或多个基因和/或SNP相关的遗传标记数据。 青光眼指标和遗传标记数据被输入到适应模型中,该模型用于产生指示受试者青光眼风险的输出。 综合来看,遗传指标和基因组数据对于青光眼的风险比孤立的两者之一更有信息。 自适应模型可以是两阶段模型,其具有第一阶段,其中通过第一自适应模型模块将个体遗传指标与基因组数据的相应部分组合以形成相应的第一输出,第二阶段中,第一输出是 通过第二自适应模式组合。 对眼底图像进行纹理分析,根据其质量对其进行分类,仅对满足质量标准的图像进行分析,以确定其是否呈现青光眼指标。 此外,图像被放入标准格式。 该系统可以包括通过组合来自多个光学杯分割技术的结果来估计光学杯的位置。 该系统可以包括通过对资金图像应用边缘检测来估计视盘的位置,排除不太可能是视盘边界点的边缘点,以及通过将椭圆拟合到剩余边缘点来估计视盘的位置 。

    Manufacturing method for thin film transistor with polysilicon active layer
    3.
    发明授权
    Manufacturing method for thin film transistor with polysilicon active layer 有权
    具有多晶硅活性层的薄膜晶体管的制造方法

    公开(公告)号:US09059214B2

    公开(公告)日:2015-06-16

    申请号:US13469567

    申请日:2012-05-11

    CPC分类号: H01L29/6675 H01L27/1277

    摘要: Embodiments of the disclosed technology relate to a method for manufacturing a thin film transistor (TFT) with a polysilicon active layer comprising: depositing an amorphous silicon layer on a substrate, and patterning the amorphous silicon layer so as to form an active layer comprising a source region, a drain region and a channel region; depositing an inducing metal layer on the source region and the drain region; performing a first thermal treatment on the active layer provided with the inducing metal layer so that the active layer is crystallized under the effect of the inducing metal; doping the source region and the drain region with a first impurity for collecting the inducing metal; and performing a second thermal treatment on the doped active layer so that the first impurity absorbs the inducing metal remained in the channel region.

    摘要翻译: 所公开的技术的实施例涉及一种用于制造具有多晶硅有源层的薄膜晶体管(TFT)的方法,包括:在衬底上沉积非晶硅层,并且对非晶硅层进行构图以形成包括源极 区域,漏极区域和沟道区域; 在所述源极区域和所述漏极区域上沉积感应金属层; 在具有诱导金属层的有源层上进行第一热处理,使得活性层在诱导金属的作用下结晶; 用第一杂质掺杂源区和漏区以收集诱导金属; 以及对掺杂的有源层进行第二热处理,使得第一杂质吸收留在沟道区中的诱导金属。

    System and method for input pin ESD protection with floating and/or biased polysilicon regions
    4.
    发明授权
    System and method for input pin ESD protection with floating and/or biased polysilicon regions 有权
    具有浮置和/或偏置多晶硅区域的输入引脚ESD保护的系统和方法

    公开(公告)号:US08319286B2

    公开(公告)日:2012-11-27

    申请号:US12979306

    申请日:2010-12-27

    IPC分类号: H01L23/60 H01L27/07

    CPC分类号: H01L27/027

    摘要: A system and method for electrostatic discharge protection. The system includes a first transistor including a first drain, a second transistor including a second drain, and a resistor including a first terminal and a second terminal. The first terminal is coupled to the first drain and the second drain. Additionally, the system includes a third transistor coupled to the second terminal and a protected system. The third transistor includes a first gate, a first dielectric layer located between the first gate and a first substrate, a first source, and a third drain. The protected system includes a fourth transistor, and the fourth transistor includes a second gate, a second dielectric layer located between the second gate and a second substrate, a second source, and a fourth drain.

    摘要翻译: 一种用于静电放电保护的系统和方法。 该系统包括第一晶体管,其包括第一漏极,包括第二漏极的第二晶体管和包括第一端子和第二端子的电阻器。 第一端子耦合到第一漏极和第二漏极。 另外,该系统包括耦合到第二终端的第三晶体管和受保护的系统。 第三晶体管包括第一栅极,位于第一栅极和第一衬底之间的第一介电层,第一源极和第三漏极。 受保护的系统包括第四晶体管,并且第四晶体管包括第二栅极,位于第二栅极和第二衬底之间的第二电介质层,第二源极和第四漏极。

    SYSTEM AND METHOD FOR INPUT PIN ESD PROTECTION WITH FLOATING AND/OR BIASED POLYSILICON REGIONS
    5.
    发明申请
    SYSTEM AND METHOD FOR INPUT PIN ESD PROTECTION WITH FLOATING AND/OR BIASED POLYSILICON REGIONS 有权
    具有浮动和/或偏置多晶硅区域的输入引脚ESD保护的系统和方法

    公开(公告)号:US20120001261A1

    公开(公告)日:2012-01-05

    申请号:US12979306

    申请日:2010-12-27

    IPC分类号: H01L23/60

    CPC分类号: H01L27/027

    摘要: A system and method for electrostatic discharge protection. The system includes a first transistor including a first drain, a second transistor including a second drain, and a resistor including a first terminal and a second terminal. The first terminal is coupled to the first drain and the second drain. Additionally, the system includes a third transistor coupled to the second terminal and a protected system. The third transistor includes a first gate, a first dielectric layer located between the first gate and a first substrate, a first source, and a third drain. The protected system includes a fourth transistor, and the fourth transistor includes a second gate, a second dielectric layer located between the second gate and a second substrate, a second source, and a fourth drain.

    摘要翻译: 一种用于静电放电保护的系统和方法。 该系统包括第一晶体管,其包括第一漏极,包括第二漏极的第二晶体管和包括第一端子和第二端子的电阻器。 第一端子耦合到第一漏极和第二漏极。 另外,该系统包括耦合到第二终端的第三晶体管和受保护的系统。 第三晶体管包括第一栅极,位于第一栅极和第一衬底之间的第一介电层,第一源极和第三漏极。 受保护的系统包括第四晶体管,并且第四晶体管包括第二栅极,位于第二栅极和第二衬底之间的第二电介质层,第二源极和第四漏极。

    Cleaning solution for an automatic biochemical analyzer
    6.
    发明授权
    Cleaning solution for an automatic biochemical analyzer 有权
    自动生化分析仪清洗液

    公开(公告)号:US08003586B2

    公开(公告)日:2011-08-23

    申请号:US12255455

    申请日:2008-10-21

    摘要: A cleaning solution for automatic biochemical analyzers includes: at least one anionic surfactant, at least one nonionic surfactant, an alkali metal hydroxide, an alkali metal citrate, and a buffering agent stabilizing the pH value above 13.0. In some embodiments, the cleaning solution provides low residual rate of proteins, low residual rate of lipids, desirable within-batch repeatability in clinical testing, low level of cross-contamination, and low level of reactant deposit after cleaning, without affecting test results of the biochemical analyzer. In some embodiments, the cleaning solution has no corrosive effects on the liquid path and reaction cup of the analyzer. The ingredients of the cleaning solution may also be biodegradable.

    摘要翻译: 用于自动生化分析仪的清洁溶液包括:至少一种阴离子表面活性剂,至少一种非离子表面活性剂,碱金属氢氧化物,碱金属柠檬酸盐和将pH值稳定在13.0以上的缓冲剂。 在一些实施方案中,清洁溶液提供了低残留率的蛋白质,低残留脂肪率,临床测试中期望的批次内重复性,交叉污染水平低,清洁后反应物沉积量低,而不影响测试结果 生化分析仪。 在一些实施方案中,清洁溶液对分析仪的液体路径和反应杯没有腐蚀作用。 清洁溶液的成分也可以是可生物降解的。

    ELECTROCHEMICAL DETECTION CELL FOR LIQUID CHROMATOGRAPHY SYSTEM
    7.
    发明申请
    ELECTROCHEMICAL DETECTION CELL FOR LIQUID CHROMATOGRAPHY SYSTEM 有权
    用于液相色谱系统的电化学检测细胞

    公开(公告)号:US20110192722A1

    公开(公告)日:2011-08-11

    申请号:US12703668

    申请日:2010-02-10

    IPC分类号: G01N27/26

    摘要: A detection cell for a chromatography system includes a cell body having an inlet, an outlet, and a counter electrode, a working electrode, a sample flow passageway extending between the inlet and the outlet and in fluid contact with the counter and working electrodes, and a palladium/noble metal reference electrode system. A method of using the detection cell is also described.

    摘要翻译: 用于色谱系统的检测电池包括具有入口,出口和对电极的电池体,工作电极,在入口和出口之间延伸并与计数器和工作电极流体接触的样品流动通道,以及 钯/贵金属参考电极系统。 还描述了使用检测单元的方法。

    Imaging system for three-dimensional reconstruction of surface profiles
    8.
    发明授权
    Imaging system for three-dimensional reconstruction of surface profiles 有权
    用于三维重建表面轮廓的成像系统

    公开(公告)号:US07676114B2

    公开(公告)日:2010-03-09

    申请号:US11305568

    申请日:2005-12-16

    IPC分类号: G01B11/24 G06K9/00

    CPC分类号: G01B11/2527

    摘要: A system for three-dimensional reconstruction of a surface profile of a surface of an object is provided that utilizes a binary pattern projected onto the surface of the object. A binary string consisting of a series of “1”s and “0”s is first created, and a binary pattern of light that is constructed in accordance with the binary string such that bright and dark bands of light of equal widths correspond to “1”s and “0”s from the binary string respectively is projected onto the surface. The binary pattern is shifted with respect to the surface multiple times, during which an image of the binary pattern illuminating the surface is obtained at each position of the binary pattern. Thereafter, a height of each predetermined point on the surface is calculated relative to a reference plane based upon the images cumulatively obtained at said predetermined point.

    摘要翻译: 提供了一种用于物体表面的表面轮廓的三维重建的系统,其利用投影到物体表面上的二进制图案。 首先创建由一系列“1”和“0”组成的二进制串,以及根据二进制串构造的二进制图案,使得相等宽度的明暗的光带对应于“ 分别将二进制串的“1”和“0”投影到表面上。 二进制图案相对于表面多次移位,在此期间,在二进制图案的每个位置处获得照亮表面的二进制图案的图像。 此后,基于在所述预定点累积获得的图像,相对于参考平面计算表面上的每个预定点的高度。

    WIRELESS COMMUNICATION APPARATUS AND WIRELESS COMMUNICATION METHOD
    9.
    发明申请
    WIRELESS COMMUNICATION APPARATUS AND WIRELESS COMMUNICATION METHOD 有权
    无线通信设备和无线通信方法

    公开(公告)号:US20090161603A1

    公开(公告)日:2009-06-25

    申请号:US12391787

    申请日:2009-02-24

    IPC分类号: H04W4/00

    摘要: A wireless communication apparatus is capable of improving communication efficiency by reducing the amount of control information transmitted. A channel quality information extraction section extracts CQI's from a received signal. An allocation control section allocates subcarriers every communication terminal apparatus and selects a modulation scheme in such a manner that required transmission rate is satisfied for each communication terminal apparatus based on required transmission rate information etc. and CQI's for communication terminal apparatus of each user. A required subcarrier number determining section decides the number of subcarriers allocated every communication terminal apparatus in such a manner as to satisfy the required transmission rate for each communication terminal apparatus based on required transmission rate information etc. of communication terminal apparatus of each user. A required subcarrier number information generating section generates information for the number of subcarriers allocated every communication terminal apparatus. A subcarrier allocation section allocates packet data to selected subcarriers. Modulating sections adaptively modulate packet data allocated to each subcarrier.

    摘要翻译: 无线通信装置能够通过减少发送的控制信息量来提高通信效率。 信道质量信息提取部分从接收到的信号中提取CQI。 分配控制部分分配每个通信终端装置的子载波,并且以每个通信终端装置的所需传输速率为基础,以每个用户的通信终端装置的CQI为依据选择调制方式。 所需的副载波号决定部基于每个用户的通信终端装置的所需传输速度信息等,决定每个通信终端装置分配的副载波的数量,以便满足每个通信终端装置所需的传输速率。 所需副载波号信息生成部生成分配给每个通信终端装置的副载波数的信息。 子载波分配部分将分组数据分配给所选择的子载波。 调制部分自适应地调制分配给每个子载波的分组数据。

    Echo Path Change Detection in a Network Echo Canceller
    10.
    发明申请
    Echo Path Change Detection in a Network Echo Canceller 审中-公开
    网络回波消除器中的回波路径变化检测

    公开(公告)号:US20090028321A1

    公开(公告)日:2009-01-29

    申请号:US12092848

    申请日:2005-11-08

    申请人: Jun Cheng

    发明人: Jun Cheng

    IPC分类号: H04B3/23 H04M9/08

    CPC分类号: H04B3/234

    摘要: An echo canceller is proposed that has an echo path change detector (10) capable of reliably distinguishing an echo path change from the condition of double talk. The echo path change detector is adapted to sample filter parameters from an FIR adaptive filter in the echo canceller, and to detect a change in intensity in a pattern formed by the sampled filter parameters. An echo path change is signalled when the degree of said pattern intensity change exceeds a predetermined level. The invention resides in the understanding that the parameters or coefficients of the adaptive FIR filter react differently to a condition of double talk or echo path change. Specifically, when these parameters are sampled and represented as an intensity pattern, a significant change in this intensity pattern over time can indicate an echo path change.

    摘要翻译: 提出了一种具有回波路径改变检测器(10)的回波消除器,其能够可靠地区分回声路径变化与双方通话的状况。 回波路径改变检测器适于从回波消除器中的FIR自适应滤波器中采样滤波器参数,并且检测由采样的滤波器参数形成的图案中的强度变化。 当所述图案强度变化的程度超过预定水平时,发出回波路径改变。 本发明的理解是,自适应FIR滤波器的参数或系数对双通道或回波路径变化的条件有不同的反应。 具体来说,当这些参数被采样并表示为强度模式时,该强度模式随时间的显着变化可以指示回波路径变化。