- 专利标题： Encapsulated cells for hormone replacement therapy
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申请号： US15014536申请日： 2016-02-03
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公开(公告)号： US09763986B2公开(公告)日： 2017-09-19
- 发明人: Emmanuel Opara , James J. Yoo , Justin M. Saul , Sittadjody Sivanandane , Anthony Atala
- 申请人： Wake Forest University Health Sciences
- 申请人地址： US NC Winston-Salem
- 专利权人： Wake Forest University Health Sciences
- 当前专利权人： Wake Forest University Health Sciences
- 当前专利权人地址： US NC Winston-Salem
- 代理机构： Myers Bigel, P.A.
- 主分类号： C12N5/07
- IPC分类号： C12N5/07 ; C12N5/00 ; C12N5/02 ; C12N5/071 ; A61K35/54 ; A61K31/565 ; A61K31/57 ; A61K9/16 ; A61K9/50
摘要：
A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
公开/授权文献
- US20160206665A1 ENCAPSULATED CELLS FOR HORMONE REPLACEMENT THERAPY 公开/授权日：2016-07-21