Invention Grant
- Patent Title: Encapsulated cells for hormone replacement therapy
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Application No.: US15014536Application Date: 2016-02-03
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Publication No.: US09763986B2Publication Date: 2017-09-19
- Inventor: Emmanuel Opara , James J. Yoo , Justin M. Saul , Sittadjody Sivanandane , Anthony Atala
- Applicant: Wake Forest University Health Sciences
- Applicant Address: US NC Winston-Salem
- Assignee: Wake Forest University Health Sciences
- Current Assignee: Wake Forest University Health Sciences
- Current Assignee Address: US NC Winston-Salem
- Agency: Myers Bigel, P.A.
- Main IPC: C12N5/07
- IPC: C12N5/07 ; C12N5/00 ; C12N5/02 ; C12N5/071 ; A61K35/54 ; A61K31/565 ; A61K31/57 ; A61K9/16 ; A61K9/50
Abstract:
A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.
Public/Granted literature
- US20160206665A1 ENCAPSULATED CELLS FOR HORMONE REPLACEMENT THERAPY Public/Granted day:2016-07-21
Information query
