- Patent Title: Intermediates for preparing triazole agonists of the APJ receptor
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Application No.: US15298748Application Date: 2016-10-20
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Publication No.: US09845310B2Publication Date: 2017-12-19
- Inventor: Ning Chen , Xiaoqi Chen , Alan C. Cheng , Richard V. Connors , Jeffrey Deignan , Paul John Dransfield , Xiaohui Du , Zice Fu , Julie Anne Heath , Daniel B. Horne , Jonathan Houze , Matthew R. Kaller , David John Kopecky , Su-Jen Lai , Zhihua Ma , Lawrence R. McGee , Julio C. Medina , Jeffrey T. Mihalic , Nobuko Nishimura , Steven H. Olson , Vatee Pattaropong , Xiaodong Wang , Kevin Yang , Mikkel V. Debenedetto , Simon J. Hedley
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard P. Friedrichsen
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D239/30 ; C07D401/14 ; C07D401/04 ; C07D413/04 ; A61K31/444 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/513 ; A61K45/06 ; C07B57/00 ; C07B59/00 ; C07D211/54 ; C07D213/71 ; C07D213/82 ; C07D239/26 ; C07D241/12 ; C07D241/24 ; C07D249/08 ; C07D405/14 ; C07D413/14 ; C07D417/14 ; C07D471/04 ; C07D401/12 ; A61K31/695 ; C07F7/08 ; A61K31/437 ; C07C311/13 ; C07D213/61 ; C07D239/34 ; C07D241/18 ; C07D295/16
Abstract:
Compounds of Formula VII, salts thereof, tautomers thereof, and salts of the tautomers are useful intermediates in the synthesis of agonists of the APJ Receptor. Compounds of Formula VII have the following structure: where the definitions of the variables are provided herein.
Public/Granted literature
- US20170035744A1 TRIAZOLE AGONISTS OF THE APJ RECEPTOR Public/Granted day:2017-02-09
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