Invention Grant
- Patent Title: Anti-PD-L1 antibodies, compositions and articles of manufacture
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Application No.: US15335278Application Date: 2016-10-26
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Publication No.: US09920123B2Publication Date: 2018-03-20
- Inventor: Bryan Irving , Henry Chiu , Heather Maecker , Sanjeev Mariathasan , Sophie M. Lehar , Yan Wu , Jeanne Cheung
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/28 ; C07K16/30 ; A61K31/7068 ; A61K39/395 ; A61K45/06 ; C07K16/10 ; C07K16/22
Abstract:
The present application relates to anti-PD-L1 antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection (e.g., acute and chronic) and tumor immunity.
Public/Granted literature
- US20170107287A1 METHODS OF USING ANTI-PD-L1 ANTIBODIES AND THEIR USE TO ENHANCE T-CELL FUNCTION TO TREAT TUMOR IMMUNITY Public/Granted day:2017-04-20
Information query
