Invention Grant
- Patent Title: Biomarker for detecting white matter stroke, containing toll-like receptor 2, and medical use of toll-like receptor 2
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Application No.: US14766759Application Date: 2013-08-30
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Publication No.: US09939451B2Publication Date: 2018-04-10
- Inventor: Byung Gon Kim , Jun Young Choi
- Applicant: AJOU UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
- Applicant Address: KR Suwon-si, Gyeonggi-do
- Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
- Current Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
- Current Assignee Address: KR Suwon-si, Gyeonggi-do
- Agency: Revolution IP, PLLC
- Priority: KR10-2013-0014520 20130208
- International Application: PCT/KR2013/007825 WO 20130830
- International Announcement: WO2014/123288 WO 20140814
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/566 ; G01N33/68 ; A61K38/08 ; C12Q1/68 ; A61K38/14 ; A61K31/716 ; A61K31/739
Abstract:
The present invention relates to a biomarker composition for detecting white matter stroke, the biomarker composition containing a toll-like receptor 2 (TLR2), and a medical use using the TLR2. The TLR2 can be used as a biomarker for white matter stroke by defending against ischemic demyelination and oligodendrocyte death, and when targeting the TLR2, ischemic white matter stroke can be treated or prevented.
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