COMPOSITION FOR TREATING OSTEOARTHRITIS
    3.
    发明公开

    公开(公告)号:US20240226111A1

    公开(公告)日:2024-07-11

    申请号:US18440990

    申请日:2024-02-14

    发明人: Siyoung Yang

    摘要: The present disclosure relates to a composition for treating osteoarthritis or eliminating senescent cells, including K-7174 that targets zinc finger MIZ domain-containing protein 1 (Zmiz1) as an active ingredient, wherein suppression of overexpression of Zmiz1 found in osteoarthritis-induced joint tissues or mice as well as suppression of expression, due to binding between K-7174 and GATA whose expression is induced by the Zmiz1 overexpression, of joint destructing factors (Mmp3, Cox2) and senescence cell promoting factors (Glb1, p16) whose expressions are increased upon the overexpression have shown effects of decreasing the progression of osteoarthritis and promoting elimination of senescent cells, such that it is possible to provide a composition including the K-7174 as an active ingredient as a treatment for osteoarthritis or an agent for eliminating senescent cells.

    Method and apparatus for digital forensic corresponding to internet of things

    公开(公告)号:US12034775B2

    公开(公告)日:2024-07-09

    申请号:US17578815

    申请日:2022-01-19

    IPC分类号: H04L9/40 G16Y30/10 H04L9/32

    摘要: The present application relates to a method and apparatus for digital forensic corresponding to an IoT (Internet of Things) terminal, the method including: performing, by an electronic device, an analysis of an Internet of Things (IoT) terminal to which digital forensics is to be performed; selecting an injection method of injecting, by the electronic device, a certificate into the IoT terminal; injecting, by the electronic device, a certificate into at least one of the IoT terminal, the electronic device, and a portable device communicating with the IoT terminal using the selected injection method; and verifying, by the electronic device, data stored in a cloud server communicating with the IoT terminal based on the injected certificate, and can also be applied to other embodiment.