- 专利标题: Silk fibroin materials and use thereof
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申请号: US13680570申请日: 2012-11-19
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公开(公告)号: US09993527B2公开(公告)日: 2018-06-12
- 发明人: David L. Kaplan , Rina Sears , Gordana Vunjak-Novakovic , Lorenz Meinel
- 申请人: Trustees of Tufts College , Massachusetts Institute of Technology
- 申请人地址: US MA Medford US MA Cambridge
- 专利权人: TRUSTEES OF TUFTS COLLEGE,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 当前专利权人: TRUSTEES OF TUFTS COLLEGE,MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- 当前专利权人地址: US MA Medford US MA Cambridge
- 代理机构: Quarles & Brady LLP
- 主分类号: A61K38/18
- IPC分类号: A61K38/18 ; A61K47/42 ; A61L27/38 ; A61L27/56 ; A61L27/22 ; A61L27/26 ; A61L27/36 ; D01D5/00 ; D01F4/02 ; C12N5/00 ; C12N5/079
摘要:
The present invention provides processes for producing porous silk fibroin scaffold material. The porous silk fibroin scaffold can be used for tissue engineering. The porosity of the silk fibroin scaffolds described herein can be adjusted as to mimic the gradient of densities found in natural tissue. Accordingly, methods for engineering of 3-dimensional tissue, e.g. bone and cartilage, using the silk fibroin scaffold material are also provided.
公开/授权文献
- US20140094410A1 SILK FIBROIN MATERIALS AND USE THEREOF 公开/授权日:2014-04-03
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