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公开(公告)号：EP3440097B1
公开(公告)日：2024-10-23
申请号：EP17718218.5
申请日：2017-04-03
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公开(公告)号：EP4423094A1
公开(公告)日：2024-09-04
申请号：EP22813058.9
申请日：2022-10-28
发明人： PINTO, Donald J.P. , SU, Shun , MATHUR, Arvind , MYERS, Michael C. , LI, Jianqing , PABBISETTY, Kumar Balashanmuga , SHAW, Scott A.
IPC分类号： C07D498/04 , C07C235/40 , C07C275/34 , A61K31/42 , A61P9/10
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公开(公告)号：EP4404930A1
公开(公告)日：2024-07-31
申请号：EP22792963.5
申请日：2022-09-22
IPC分类号： A61K31/501 , A61K31/506 , A61P17/14 , A61K9/00
CPC分类号： A61K31/501 , A61K31/506 , A61P17/14 , A61K9/0053 , A61K9/0014
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公开(公告)号：EP3791183B1
公开(公告)日：2024-07-24
申请号：EP19729943.1
申请日：2019-05-09
IPC分类号： G01N33/543 , G01N33/68
CPC分类号： G01N33/54393 , G01N33/6851 , G01N2333/91220130101
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公开(公告)号：EP4344695A3
公开(公告)日：2024-06-05
申请号：EP24157510.9
申请日：2019-05-10
CPC分类号： A61J1/20 , A61J1/2058 , A61J1/2068 , A61J1/2089 , A61J3/002 , A61M5/1408 , A61M5/1409 , A61J1/16 , A61M5/14248 , A61M2005/1426820130101 , A61M2209/04520130101 , A61M5/1413
摘要： In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.
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7.发明公开
公开(公告)号：EP4373839A1
公开(公告)日：2024-05-29
申请号：EP22846765.0
申请日：2022-07-18
发明人： CUI, Honggang , LI, Yi , STERN, David , XU, XuanKuo , LOCK, Lye, Lin , MILLS, Jason , GHOSE, Sanchayita , LI, Zheng Jian
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公开(公告)号：EP4364737A2
公开(公告)日：2024-05-08
申请号：EP24159615.4
申请日：2021-10-18
发明人： LUO, Guanglin , CHEN, Jie , DZIERBA, Carolyn Diane , FRENNESSON, David B. , GUO, Junqing , HART, Amy C. , HU, Xirui , MERTZMAN, Michael E. , PATTON, Matthew Reiser , SHI, Jianliang , SPERGEL, Steven H. , VENABLES, Brian Lee , WU, Yong-Jin , XIAO, Zili , YANG, Michael G.
IPC分类号： A61K31/444
CPC分类号： C07D471/04 , A61P29/00 , A61P9/04 , A61P17/06 , A61P25/28
摘要： Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof,
are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.-
9.发明公开
公开(公告)号：EP4359438A1
公开(公告)日：2024-05-01
申请号：EP22738290.0
申请日：2022-06-17
发明人： BINDRA, Dilbir Singh , DEAR, Barton J. , HU, Yue , MONDAL SIERRA, Ismahr-ehl , MORE, Haresh Tukaram , PAN, Duohai , WU, Yongmei
IPC分类号： C07K16/28 , A61K39/395 , A61K9/19 , A61K47/26
CPC分类号： C07K16/2818 , C07K2317/7420130101 , C07K2319/0020130101 , C07K2319/5020130101 , A61K39/39591 , C07K2317/9020130101 , A61K9/19 , A61K47/26 , A61K47/183 , A61K9/0019
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公开(公告)号：EP4054511B1
公开(公告)日：2024-03-13
申请号：EP20819921.6
申请日：2020-11-02
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