利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

10 条记录 (耗时 0.011 秒)

    PROCEDE DE TRAITEMENT DE DONNEES D'IMAGERIE MOLECULAIRE ET SERVEUR DE DONNEES CORRESPONDANT
    2.
    发明公开
    PROCEDE DE TRAITEMENT DE DONNEES D'IMAGERIE MOLECULAIRE ET SERVEUR DE DONNEES CORRESPONDANT 审中-公开
    ZERGEHER​​RIGER DATENSERVER VERFAHREN ZUR VERARBEITUNG BILDGEBUNGSDATEN

    公开(公告)号：EP3092589A1

    公开(公告)日：2016-11-16

    申请号：EP15701558.7

    申请日：2015-01-09

    申请人： Imabiotech

    发明人： PAMELARD, Fabien ,  STAUBER, Jonathan M.

    IPC分类号： G06F19/26 ,  G06F19/28

    CPC分类号： G06K9/0014 ,  G06F19/26 ,  G06F19/28 ,  G06T3/40 ,  G06T7/0014 ,  G06T7/337 ,  G06T7/90 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/30024 ,  H01J49/0036

    摘要： The invention relates mainly to a method for processing a plurality of spectral datasets (J1-Jn) intended for being used by a molecular imaging method or a method for recording a plurality of spectral datasets (J1-Jn), each spectral dataset (J1-Jn) being defined by a set of spatial positions (Xi, Yj) each of which is associated with a molecular spectrum with at least two dimensions containing a set of molecular information (S(Xi, Yj)), characterised in that it comprises in particular the following steps: for each dataset (J1-Jn), cutting the molecular spectrum associated with each position (Xi, Yj) into a plurality of spectrum segments (T1-Tm); inserting the segments (T1-Tm) obtained for each position (Xi, Yj) of each dataset (J1-Jn) into a database (BDD); selecting in the database (BDD), following a request relating to molecular information of interest, the one or more segments (T1-Tm) containing the molecular information of interest; and selecting, within each segment (T1-Tm), said molecular information of interest.

    摘要翻译： 一种用于处理旨在由分子成像方法或用于记录多个光谱数据集（J1-Jn）的方法使用的多个光谱数据集（J1-Jn）的方法，每个光谱数据集（J1-Jn）由 一组空间位置（Xi，Yj），其每一个与具有至少两个维度的分子谱相关联，所述分子谱包含一组分子信息（S（Xi，Yj）），该方法特别包括以下步骤：对于每个 数据集（J1-Jn），将与每个位置（Xi，Yj）相关联的分子谱切割成多个频谱段（T1-Tm）; 将每个数据集（J1-Jn）的每个位置（Xi，Yj）获得的段（T1-Tm）插入到数据库（BDD）中; 根据感兴趣的分子信息的请求在数据库（BDD）中选择包含感兴趣的分子信息的一个或多个片段（T1-Tm）; 并在每个片段（T1-Tm）内选择感兴趣的分子信息。

    METHOD TO EVALUATE THE TISSUE TARGETING OF A MOLECULE OF INTEREST
    3.
    发明公开
    METHOD TO EVALUATE THE TISSUE TARGETING OF A MOLECULE OF INTEREST 审中-公开
    VERFAHREN ZUR BEURTEILUNG DES GEWEBETARGETING EINESMOLEKÜLSVON INTERESSE

    公开(公告)号：EP2959294A1

    公开(公告)日：2015-12-30

    申请号：EP14706597.3

    申请日：2014-02-25

    申请人： Imabiotech

    发明人： HAMM, Grégory ,  STAUBER, Jonathan

    IPC分类号： G01N33/50

    CPC分类号： G01N33/5035 ,  A61K49/0008 ,  G01N33/5082

    摘要： The invention relates to a method for evaluating whether a molecule of interest binds or is incorporated in at least one target tissue, comprising visualizing and comparing the distribution of the molecule of interest and of at least one control compound within the target tissue or on the target tissue surface of at least one animal that has previously received the molecule of interest and/or the control compound. Advantageously, the distribution of the molecule of interest is visualized and compared with the distribution of positive and negative compounds using mass spectrometry imaging on the surface of the target tissue.

    摘要翻译： 本发明涉及用于评估目的分子是否结合或并入至少一个靶组织中的方法，所述至少一个靶组织包括观察和比较目标组织中或目标上的目标分子和至少一种对照化合物的分布 至少一种先前接受目标分子和/或对照化合物的动物的组织表面。 有利地，将目标分子的分布可视化，并使用质谱成像在目标组织的表面上与正和负化合物的分布进行比较。

    METHOD FOR DETECTING AND QUANTIFYING A TARGET MOLECULE IN A SAMPLE
    7.
    发明公开
    METHOD FOR DETECTING AND QUANTIFYING A TARGET MOLECULE IN A SAMPLE 审中-公开
    一种用于在样品检测和定量目标分子

    公开(公告)号：EP2689251A1

    公开(公告)日：2014-01-29

    申请号：EP12709114.8

    申请日：2012-03-19

    申请人： Imabiotech

    发明人： STAUBER, Jonathan ,  PAMELARD, Fabien ,  BONNEL, David ,  HAMM, Grégory

    IPC分类号： G01N33/68

    CPC分类号： H01J49/164 ,  G01N33/4833 ,  G01N33/6851 ,  H01J49/0004 ,  H01J49/0027

    摘要： The invention relates to a method for identifying and quantifying by mass spectrometry imaging at least one target analyte in a tissue sample, comprising the following steps: a) depositing the tissue sample to be analyzed on a support; b) analyzing the sample by mass spectrometry imaging, so as to obtain the mass spectrum of the target analyte in said tissue sample; c) weighting a signal associated with the mass spectrum of the target analyte in said tissue sample by a tissue extinction coefficient (TEC) specific to the target analyte and to the tissue sample which is obtained by using a control tissue sample; and d) using the weighted signal of the target analyte to determine the quantity of target analyte in the tissue sample.

    METHOD TO EVALUATE THE TISSUE TARGETING OF A MOLECULE OF INTEREST
    9.
    发明授权
    METHOD TO EVALUATE THE TISSUE TARGETING OF A MOLECULE OF INTEREST 有权

    公开(公告)号：EP2959294B1

    公开(公告)日：2018-08-08

    申请号：EP14706597.3

    申请日：2014-02-25

    申请人： Imabiotech

    发明人： HAMM, Grégory ,  STAUBER, Jonathan

    IPC分类号： G01N33/50

    CPC分类号： G01N33/5035 ,  A61K49/0008 ,  G01N33/5082

    摘要： The invention relates to a method for evaluating whether a molecule of interest binds or is incorporated in at least one target tissue, comprising visualizing and comparing the distribution of the molecule of interest and of at least one control compound within the target tissue or on the target tissue surface of at least one animal that has previously received the molecule of interest and/or the control compound. Advantageously, the distribution of the molecule of interest is visualized and compared with the distribution of positive and negative compounds using mass spectrometry imaging on the surface of the target tissue.