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公开(公告)号：EP0776324A1
公开(公告)日：1997-06-04
申请号：EP95928323.0
申请日：1995-08-04
申请人： Abbott Laboratories
发明人： WINN, Martin , BOYD, Steven, A. , HUTCHINS, Charles, W. , JAE, Hwan-Soo , TASKER, Andrew, S. , VONGELDERN, Thomas, W. , KESTER, Jeffrey, A. , SORENSEN, Bryan, K.
IPC分类号： C07D , A61K31 , A61P9 , A61P29 , A61P35 , A61P43 , C07D207 , C07D401 , C07D403 , C07D405 , C07D413 , C07D419 , C07D471 , C07F9
CPC分类号： C07D401/04 , C07D207/16 , C07D403/04 , C07D405/04 , C07D405/14 , C07F9/5722 , C07F9/592
摘要： A compound of formula (I) or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
摘要翻译： 公开了式（I）化合物或其药学上可接受的盐，以及其制备方法和中间体以及拮抗内皮素的方法。
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2.发明授权NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS 失效新苯并-1,3-二唑和取代的苯并呋喃PYRROLIDINEDERIVATE ALS内皮素拮抗剂
公开(公告)号：EP0885215B1
公开(公告)日：2006-04-19
申请号：EP97905816.1
申请日：1997-02-12
申请人： ABBOTT LABORATORIES
发明人： WINN, Martin , BOYD, Steven, A. , HUTCHINS, Charles, W. , JAE, Hwan-Soo , TASKER, Andrew, S. , VON GELDERN, Thomas, W. , KESTER, Jeffrey, A. , SORENSEN, Bryan, K. , SZCZEPANKIEWICZ, Bruce, G. , HENRY, Kenneth, J., Jr. , LIU, Gang , WITTENBERGER, Steven, J. , KING, Steven, A.
IPC分类号： C07D405/04 , C07D207/16 , A61K31/40 , C07D405/14 , C07F9/59 , C07F9/572 , C07D401/04
CPC分类号： C07D401/04 , C07D207/16 , C07D405/04 , C07D405/12 , C07D405/14 , Y02P20/55
摘要： A compound of formula (I), or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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3.发明公开NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS 失效新苯并-1,3-二唑和取代的苯并呋喃PYRROLIDINEDERIVATE ALS内皮素拮抗剂
公开(公告)号：EP0885215A1
公开(公告)日：1998-12-23
申请号：EP97905816.0
申请日：1997-02-12
申请人： Abbott Laboratories
发明人： WINN, Martin , BOYD, Steven, A. , HUTCHINS, Charles, W. , JAE, Hwan-Soo , TASKER, Andrew, S. , VON GELDERN, Thomas, W. , KESTER, Jeffrey, A. , SORENSEN, Bryan, K. , SZCZEPANKIEWICZ, Bruce, G. , HENRY, Kenneth, J., Jr. , LIU, Gang , WITTENBERGER, Steven, J. , KING, Steven, A.
IPC分类号： A61K31 , A61P1 , A61P7 , A61P9 , A61P11 , A61P13 , A61P25 , A61P43 , C07D207 , C07D211 , C07D401 , C07D403 , C07D405 , C07D409 , C07D413 , C07D417 , C07D419 , C07D453 , C07D471 , C07D491 , C07F9
CPC分类号： C07D401/04 , C07D207/16 , C07D405/04 , C07D405/12 , C07D405/14 , Y02P20/55
摘要： A compound of formula (I), or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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公开(公告)号：EP0776324B1
公开(公告)日：2002-06-12
申请号：EP95928323.5
申请日：1995-08-04
申请人： Abbott Laboratories
发明人： WINN, Martin , BOYD, Steven, A. , HUTCHINS, Charles, W. , JAE, Hwan-Soo , TASKER, Andrew, S. , VONGELDERN, Thomas, W. , KESTER, Jeffrey, A. , SORENSEN, Bryan, K.
IPC分类号： C07D405/04 , C07D207/16 , A61K31/40 , C07D405/14 , C07F9/59 , C07F9/572
CPC分类号： C07D401/04 , C07D207/16 , C07D403/04 , C07D405/04 , C07D405/14 , C07F9/5722 , C07F9/592
摘要： A compound of formula (I) or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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5.发明公开PYRROLIDINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGOISTS 失效吡咯烷-3-羧酸衍生物及其作为内皮素拮抗剂的用途
公开(公告)号：EP1003740A2
公开(公告)日：2000-05-31
申请号：EP98937139.8
申请日：1998-07-27
申请人： Abbott Laboratories
发明人： WINN, Martin , BOYD, Steven, A. , HUTCHINS, Charles, W. , JAE, Hwan-Soo , TASKER, Andrew, S. , von GELDERN, Thomas, W. , KESTER, Jeffrey, A. , SORENSEN, Bryan, K. , SZCZEPANKIEWICZ, Bruce, G. , HENRY, Kenneth, J. , LIU, Gang , WITTENBERGER, Steven, J. , KING, Steven, A.
IPC分类号： C07D405/00
CPC分类号： C07D207/27 , C07D207/16 , C07D403/04 , C07D405/04 , C07D405/14 , C07D413/14 , C07D417/14
摘要： A compound of formula (I), or a pharmaceutically acceptable salt thereof, is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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