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公开(公告)号：EP1549343A4
公开(公告)日：2006-03-15
申请号：EP03754734
申请日：2003-09-16
申请人： ABGENIX INC , CURAGEN CORP
IPC分类号： C07K16/22 , G01N33/68 , A61K39/395 , A61K39/44 , A61P13/12 , G01N33/53 , G01N33/533 , G01N33/534 , G01N33/535
CPC分类号： G01N33/6893 , A61K2039/505 , C07K16/22 , C07K2317/21 , C07K2317/73 , G01N2333/49 , G01N2800/347
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2.发明公开ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF 有权抗EGF（表皮生长因子）受体 - 抗体展望及其用途的缺失突变体
公开(公告)号：EP1639092A4
公开(公告)日：2009-06-03
申请号：EP04777147
申请日：2004-06-25
申请人： ABGENIX INC
发明人： WEBER RICHARD , FENG XIAO , FOORD ORIT , GREEN LARRY , GUDAS JEAN , KEYT BRUCE , LIU YING , RATHANASWAMI PALANI , RAYA ROBERT , YANG XIAO DONG , CORVALAN JOSE , FOLTZ IAN , JIA XIAO-CHI , KANG JASPAL , KING CHADWICK T , KLAKAMP SCOTT L , SU QIAOJUAN JANE
IPC分类号： A61K39/395 , A61K47/48 , C07K16/22 , C07K16/28 , C07K17/00 , C12N20060101 , C12N5/06 , G01N33/53
CPC分类号： C07K16/30 , A61K47/6803 , A61K47/6849 , A61K47/6897 , A61K2039/505 , B82Y5/00 , C07K16/2863 , C07K2317/21 , C07K2317/34 , C07K2317/77 , C07K2317/92 , Y10S435/81
摘要： The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.
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3.发明公开ANTIBODIES DIRECTED TO THE DELETION MUTANTS OF EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREOF 有权表皮生长因子受体及其应用的抗体缺失突变体
公开(公告)号：EP1638606A4
公开(公告)日：2009-06-03
申请号：EP04777034
申请日：2004-06-25
申请人： ABGENIX INC
发明人： WEBER RICHARD , FENG XIAO , FOORD ORIT , GREEN LARRY , GUDAS JEAN , KEYT BRUCE , LIU YING , RATHANASWAMI PALANI , RAYA ROBERT , YANG XIAO DONG , CORVALAN JOSE , FOLTZ IAN , JIA XIAO-CHI , KANG JASPAL , KING CHADWICK T , KLAKAMP SCOTT L , SU QIAOJUAN JANE
IPC分类号： A61K39/395 , A61K47/48 , C07K16/22 , C07K16/28 , C07K17/00 , C12N20060101 , C12N5/06 , G01N33/53
CPC分类号： C07K16/30 , A61K47/6803 , A61K47/6849 , A61K47/6897 , A61K2039/505 , B82Y5/00 , C07K16/2863 , C07K2317/21 , C07K2317/34 , C07K2317/77 , C07K2317/92 , Y10S435/81
摘要： The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant, EGFRvIII. The invention also relates to human monoclonal antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to EGFRvIII. Diagnostic and therapeutic formulations of such antibodies, and immunoconjugates thereof, are also provided.
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