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公开(公告)号：EP1670798A1
公开(公告)日：2006-06-21
申请号：EP04820599.1
申请日：2004-09-30
申请人： Altana Pharma AG
发明人： FUCHSS, Thomas , BOER, Rainer , MARX, Degenhard , ULRICH, Wolf-Ruediger , ELTZE, Manfrid , NAVE, Ruediger , STRUB, Andreas , GRAEDLER, Ulrich
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, R3 and R4 the meanings as given in the description are novel effective iNOS inhibitors.
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公开(公告)号：EP1673371A1
公开(公告)日：2006-06-28
申请号：EP04787261.9
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： ULRICH, Wolf-Ruediger , FUCHSS, Thomas , MARTIN, Thomas , BOER, Rainer , STRUB, Andreas , ELTZE, Manfrid , LEHNER, Martin , MARX, Degenhard
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, Het1 and A have the meanings as given in the description are novel effective iNOS inhibitors.
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公开(公告)号：EP1682148A1
公开(公告)日：2006-07-26
申请号：EP04817396.7
申请日：2004-10-29
申请人： ALTANA Pharma AG
IPC分类号： A61K31/519 , A61K31/195
CPC分类号： A61K45/06 , A61K31/195 , A61K31/198 , A61K31/519 , A61K2300/00
摘要： The invention describes the use of Tetrahydrobiopterin (BH4) or derivatives thereof for the treatment of COPD. In a preferred embodiment, BH4 or derivatives thereof are combined with arginine or derivatives thereof.
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公开(公告)号：EP1670796A1
公开(公告)日：2006-06-21
申请号：EP04787262.7
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： ULRICH, Wolf-Ruediger , FUCHSS, Thomas , MARTIN, Thomas , BOER, Rainer , STRUB, Andreas , ELTZE, Manfrid , LEHNER, Martin
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00 , C07D519/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors.
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5.发明公开N-4-(6-(HETEO)ARYL-PYRIMIDIN-4-YLAMINOPHENYL)-BENZENESULFONAMIDES AS KINASE INHIBITORS 审中-公开N-4-（6-（HETEO）ARYLPYRIMIDIN-4-YLAMINOPHENYL）苯二甲酰胺ALS激酶基因
公开(公告)号：EP1709007A1
公开(公告)日：2006-10-11
申请号：EP05701549.7
申请日：2005-01-19
申请人： Altana Pharma AG
发明人： BARSIG, Johannes , BAUDLER, Monika , BUNDSCHUH, Daniela , GANTNER, Florian , GRAEDLER, Ulrich , HEIT, Isabelle , MARTIN, Thomas , SCHAEFER, Michaela , SCHLEMMINGER, Imre , STADLWIESER, Josef , ULRICH, Wolf-Ruediger
IPC分类号： C07D239/42 , C07D409/14 , C07D403/04 , C07D405/04 , A61K31/505 , A61K31/506 , A61P35/00 , A61P37/00
CPC分类号： C07D239/42 , C07D403/04 , C07D405/04 , C07D409/14
摘要： Compounds of a certain formula 1 in which R1 and R2 have the meanings indicated in the description are novel kinase inhibitors. Formula (1), in which R1 is phenyl, phenyl substituted by R3 and/or R4, naphthalenyl, naphthalenyl substituted by R5 and/or R6, aryl1, aryl1 substituted by R7 and/or R8, R9, R10 or R11, R2 is phenyl, phenyl substituted by R12 and/or R13, naphthalenyl, naphthalenyl substituted by R14 and/or R15, aryl2, aryl2 substituted by R16 and/or R17 or a radical selected from Formula (2).
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公开(公告)号：EP1675854A1
公开(公告)日：2006-07-05
申请号：EP04787263.5
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： ULRICH, Wolf-Ruediger , FUCHSS, Thomas , MARTIN, Thomas , BOER, Rainer , STRUB, Andreas , ELTZE, Manfrid , LEHNER, Martin
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04 , A61K31/437
摘要： The compounds of formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors.
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7.发明授权IMIDAZO 4,5-B QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS 有权IMIDAZO¬4,5-B |喹啉及其作为抑制剂诱导型NO合酶
公开(公告)号：EP1599473B1
公开(公告)日：2006-09-20
申请号：EP04713907.6
申请日：2004-02-24
申请人： ALTANA Pharma AG
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： The compounds of formula I In which R1, R2, R3 and A have the meanings as given In the description are novel effective INOS Inhibitors.
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8.发明公开IMIDAZO(4,5-B)PYRIDINE-DERIVATIVES AS INDUCIBLE NO-SYNTHASE INHIBITORS 有权咪唑并[4,5-b]吡啶衍生物作为可诱导的NO合酶的抑制剂
公开(公告)号：EP1675853A1
公开(公告)日：2006-07-05
申请号：EP04787257.7
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： FUCHSS, Thomas , BOER, Rainer , ULRICH, Wolf-Ruediger , ELTZE, Manfrid , MARX, Degenhard , GRAEDLER, Ulrich
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, R3, R4 and R11 the meanings as given in the description are novel effective iNOS inhibitors.
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9.发明公开IMIDAZO 4,5-B QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS 有权咪唑并[4,5-B]喹啉衍生物和它们作为抑制剂的诱导型NO合成酶使用
公开(公告)号：EP1599473A1
公开(公告)日：2005-11-30
申请号：EP04713907.6
申请日：2004-02-24
申请人： ALTANA Pharma AG
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： The compounds of formula I In which R1, R2, R3 and A have the meanings as given In the description are novel effective INOS Inhibitors.
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