-
公开(公告)号：EP1144348A2
公开(公告)日：2001-10-17
申请号：EP99943016.8
申请日：1999-09-21
发明人： DANVY, Denis , MONTEIL, Thierry , PLAQUEVENT, Jean-Christophe , DUHAMEL, Pierre , DUHAMEL, Lucette , NOEL, Nadine , GROS, Claude , CHAMARD, Olivier , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie
IPC分类号： C07C1/00
CPC分类号： C07C323/25 , C07C327/30 , C07D213/64 , C07D317/64
摘要： The invention concerns LTA4 hydrolase inhibiting compounds of formula (I). It also concerns their therapeutic, in particular anti-inflammatory, applications.
-
公开(公告)号：EP1144348A3
公开(公告)日：2002-09-11
申请号：EP99943016.8
申请日：1999-09-21
发明人： DANVY, Denis , MONTEIL, Thierry , PLAQUEVENT, Jean-Christophe , DUHAMEL, Pierre , DUHAMEL, Lucette , NOEL, Nadine , GROS, Claude , CHAMARD, Olivier , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie
IPC分类号： C07C1/00
CPC分类号： C07C323/25 , C07C327/30 , C07D213/64 , C07D317/64
-
3.发明授权DERIVATIVES OF 1-N-AZACYCLOALKYL-3-PHENOXYPROPANE USEFUL FOR THE PREPARATION OF PSYCHOTROPIC MEDICAMENTS 有权用于生产精神药品的1-N-氮杂环烷基-3-苯氧合适的衍生物
公开(公告)号：EP1874746B1
公开(公告)日：2015-11-18
申请号：EP06744550.2
申请日：2006-04-25
申请人： BIOPROJET
发明人： BERTRAND, Isabelle , CAPET, Marc , LECOMTE, Jeanne-Marie , LEVOIN, Nicolas , LIGNEAU, Xavier , POUPARDIN-OLIVIER, Olivia , ROBERT, Philippe , SCHWARTZ, Jean-Charles , LABEEUW, Olivier
IPC分类号： C07D295/088 , C07D213/30 , C07D211/68 , C07D333/16 , C07D211/14 , C07D401/10 , A61K31/40 , A61K31/44 , A61K31/381 , A61K31/5377
CPC分类号： C07D213/30 , C07D207/20 , C07D207/30 , C07D207/335 , C07D211/22 , C07D211/42 , C07D211/46 , C07D211/68 , C07D211/70 , C07D213/61 , C07D213/64 , C07D213/89 , C07D231/12 , C07D295/088 , C07D295/192 , C07D333/16 , C07D333/20 , C07D401/12 , C07D401/14 , C07D409/12 , C07D413/12
-
4.发明公开A COMBINATION OF ADRENALIN WITH AN ANTIDEPRESSANT FOR USE IN THE TREATMENT OF SHOCKS 有权肾上腺素与用于过敏性休克的治疗中使用的抗抑郁药组合
公开(公告)号：EP2903607A1
公开(公告)日：2015-08-12
申请号：EP13771500.9
申请日：2013-10-02
申请人： Bioprojet
发明人： SCHWARTZ, Jean-Charles , LIGNEAU, Xavier , LANDAIS, Laurent, François, Gérard , PERRIN, David , LECOMTE, Jeanne-Marie
IPC分类号： A61K31/165 , A61K31/335 , A61K31/55 , A61K45/06 , A61P37/08
CPC分类号： A61K31/335 , A61K9/0019 , A61K31/137 , A61K45/06 , A61K2300/00
摘要： The present invention concerns a novel combination of adrenalin with an antidepressant and its use as a pharmaceutical composition for the treatment of shocks. The pharmaceutical composition is to be administered by injection.
摘要翻译： 本发明涉及具有抗抑郁和其作为冲击的治疗的药物组合物中使用的新颖的肾上腺素组合。 所述药物组合物通过注射给药。
-
公开(公告)号：EP1874747A1
公开(公告)日：2008-01-09
申请号：EP06744570.0
申请日：2006-04-26
申请人： BIOPROJET
发明人： BERTRAND, Isabelle , CAPET, Marc , LECOMTE, Jeanne-Marie , LEVOIN, Nicolas , LIGNEAU, Xavier , POUPARDIN-OLIVIER, Olivia , ROBERT, Philippe , SCHWARTZ, Jean-Charles
IPC分类号： C07D295/088 , C07D307/79 , C07D317/54 , C07D319/18 , A61K31/40 , A61K31/445 , A61P25/00
CPC分类号： C07D295/088 , C07D307/79 , C07D317/54 , C07D319/18
摘要： The present patent application concerns new compounds of formula (I) with R1 and R2 taken together with the nitrogen atom to which they are attached, form a saturated nitrogen-containing ring, A is a saturated C1 -4 alkylene and B a C3-4 alkylene or alkenylene chain; their preparation and their use as a H3 receptor ligand for treating e.g. CNS disorders like Alzheimer's disease.
-
6.发明公开
公开(公告)号：EP1863487A2
公开(公告)日：2007-12-12
申请号：EP06744466.1
申请日：2006-03-30
申请人： BIOPROJET
IPC分类号： A61K31/4453 , A61P25/16 , A61P25/28
CPC分类号： A61K31/4453
摘要： The present invention provides new method of treatment of Parkinson's disease, obstructive sleep apnea, narcolepsy, dementia with Lewy bodies, vascular dementia with non-imidazole alkylamine derivatives that constitute antagonists of the H3-receptors of histamine.
-
7.发明公开NEW COMBINATIONS OF AN ANTI EMETIC AGENT AND AN ENKEPHALINASE INHIBITOR 有权有5-HT3受体拮抗剂或消旋卡多曲的新组合DEXECADOTRIL
公开(公告)号：EP1718337A1
公开(公告)日：2006-11-08
申请号：EP05702484.6
申请日：2005-02-14
申请人： BIOPROJET
IPC分类号： A61K45/06 , A61K31/4178 , A61K31/439 , A61K31/265 , A61P1/12
CPC分类号： A61K45/06 , A61K31/265 , A61K31/4178 , A61K31/439 , A61K2300/00
摘要： The present invention concerns new combinations of an anti-emetic agent and an enkephalinase inhibitor, the uses of said combinations for treating diarrhea and/or gastroenteritis.
-
公开(公告)号：EP1165491A1
公开(公告)日：2002-01-02
申请号：EP00917145.5
申请日：2000-04-06
发明人： DANVY, Denis , MONTEIL, Thierry , PLAQUEVENT, Jean-Christophe , DUHAMEL, Pierre , DUHAMEL, Lucette , NOEL, Nadine , GROS, Claude , CHAMARD, Olivier , SCHWARTZ, Jean-Charles , LECOMTE, Jeanne-Marie , PIETTRE, Serge
IPC分类号： C07C229/12 , C07F9/38 , A61P29/00
CPC分类号： C07F9/3808 , C07C45/30 , C07C47/277 , C07C229/08 , C07C251/02 , C07F9/4006
摘要： The invention concerns compounds inhibiting LTA4 hydrolase of formula (I). The invention also concerns their therapeutic, in particular anti-inflammatory, applications.
摘要翻译： 本发明涉及抑制式（I）的LTA4水解酶的化合物。 本发明还涉及它们的治疗，特别是抗炎应用。
-
9.发明公开NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS 有权治疗用途组胺H3受体配体烷基胺中不含咪唑
公开(公告)号：EP1100503A2
公开(公告)日：2001-05-23
申请号：EP99941543.3
申请日：1999-07-29
发明人： SCHWARTZ, Jean-Charles , ARRANG, Jean-Michel , GARBARG, Monique , LECOMTE, Jeanne-Marie , LIGNEAU, Xavier , SCHUNACK, Walter, G. , STARK, Holger , GANELLIN, Charon, Robin , LEURQUIN, Fabien , SIGURD, Elz
IPC分类号： A61K31/4453 , A61K31/40 , A61K31/445 , A61K31/138
CPC分类号： C07D213/74 , A61K31/396 , A61K31/397 , A61K31/40 , A61K31/445 , A61K31/55 , C07B2200/07 , C07C217/16 , C07C217/20 , C07C217/22 , C07C251/48 , C07C255/54 , C07C2602/10 , C07D207/20 , C07D211/58 , C07D211/60 , C07D211/62 , C07D211/70 , C07D215/38 , C07D215/46 , C07D239/42 , C07D271/06 , C07D277/82 , C07D295/03 , C07D295/088 , C07D295/096 , C07D295/13 , C07D295/185
摘要： Use of a compound of formula (A), wherein: W is a residue which imparts antagonistic and/or agonistic activity at histamine H3-receptors when attached to an imidazole ring in 4(5) position; R?1 and R2¿ may be identical or different and represent each independently a lower alkyl or cycloalkyl, or taken together with the nitrogen atom to which they are attached, a saturated nitrogen-containing ring (i) as defined, a non-aromatic unsaturated nitrogen-containing ring (ii) as defined, a morpholino group, or a N-substituted piperazino group as defined for preparing medicaments acting as antagonists and/or agonists at the H¿3?-receptors of histamine.
-
公开(公告)号：EP4146214A1
公开(公告)日：2023-03-15
申请号：EP21722486.4
申请日：2021-05-04
申请人： BIOPROJET Pharma
发明人： LECOMTE, Jeanne-Marie , SCHWARTZ, Jean Charles , BERREBI-BERTRAND, Isabelle , KRIEF, Stéphane , LIGNEAU, Xavier , LECOMTE, Isabelle
IPC分类号： A61K31/495 , A61P25/00 , A61P25/16 , A61P25/28
-
-
-
-
-
-
-
-
-
搜索结果
59 条记录 (耗时 0.037 秒)
