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1.发明公开REPEAT SEQUENCE PROTEIN POLYMER ACTIVE AGENT CONJUGATES, METHODS AND USES 审中-公开维生素SEQUENZ-PROTEIN-聚合物-WIRKSTOFF-KONJUGATE，VERFAHREN UND VERWENDUNGEN
公开(公告)号：EP1633382A2
公开(公告)日：2006-03-15
申请号：EP04752348.5
申请日：2004-05-14
IPC分类号： A61K38/00
CPC分类号： A61K8/64 , A61K38/00 , A61K47/59 , A61K47/64 , A61K2800/57 , A61Q13/00 , A61Q17/04 , C07K14/21 , C07K14/415 , C07K14/43504 , C07K14/43586 , C07K14/4716 , C07K14/4727 , C07K14/4741 , C07K14/78 , C07K2319/00 , C08H1/00 , C08H1/06
摘要： Biomolecular conjugates are provided which comprise the conjugation product of a repeat sequence protein polymer and at least one active agent. Additional aspects provide methods for their manufacture and various industrial and consumer applications.
摘要翻译： 提供了包含重复序列蛋白质聚合物和至少一种活性剂的缀合产物的生物分子缀合物。 其他方面提供了其制造方法和各种工业和消费者应用。
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公开(公告)号：EP1042501B2
公开(公告)日：2011-03-30
申请号：EP98966092.3
申请日：1998-12-23
发明人： SCHELLENBERGER, Volker , NAKI, Donald, P. , COLLIER, Katherine, D. , KELLIS, James, T., Jr. , NADHERNY, Joanne
IPC分类号： C12Q1/00
CPC分类号： C12Q1/00
摘要： An improved method for assaying the wash performance of new enzymes and/or new detergent formulations by comparing performance of enzyme cleaning effectiveness on washed soiled swatch cloths.
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3.发明授权METHOD FOR TREATING CELLULOSE CONTAINING FABRICS USING TRUNCATED CELLULASE ENZYME COMPOSITIONS 失效法纤维素织物与简明纤维素酶ENZUME含组合物治疗
公开(公告)号：EP0807193B1
公开(公告)日：2007-01-03
申请号：EP96905208.3
申请日：1996-01-29
发明人： FOWLER, Timothy , CLARKSON, Kathleen, A. , WARD, Michael , COLLIER, Katherine, D. , LARENAS, Edmund
CPC分类号： D06P5/158 , A23K20/189 , C11D3/38645 , C12N9/2437 , C12N15/80 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , D06M16/003 , D06P5/02 , D06P5/137 , Y10T442/20
摘要： Improved methods of treating cellulose containing fabrics with cellulase comprising contacting the cellulose fabrics with truncated cellulase enzyme. Treatment of cellulose containing fabrics with cellulase core domains of the invention are disclosed as offering specific advantages of reduced redeposition of dye and increased abrasion.
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4.发明授权MULTIPLY-SUBSTITUTED PROTEASE VARIANTS WITH ALTERED NET CHARGE FOR USE IN DETERGENTS 无效多的取代的蛋白酶变种改进净电荷用于洗涤剂
公开(公告)号：EP1025240B1
公开(公告)日：2005-12-28
申请号：EP98955111.4
申请日：1998-10-23
发明人： POULOSE, Ayrookaran, J. , SCHELLENBERGER, Volker , KELLIS, James, T., Jr. , PAECH, Christian , NADHERNY, Joanne , NAKI, Donald, P. , CALDWELL, Robert, M. , COLLIER, Katherine, D.
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
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公开(公告)号：EP1025239A2
公开(公告)日：2000-08-09
申请号：EP98953936.6
申请日：1998-10-23
发明人： SCHELLENBERGER, Volker , KELLIS, James, T., Jr. , PAECH, Christian , NADHERNY, Joanne , NAKI, Donald, P. , POULOSE, Ayrookaran, J. , COLLIER, Katherine, D. , CALDWELL, Robert, M. , BAECK, André, C.
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
摘要： Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue correspond to positions 62, 212, 230, 232, 252 and 257 of Bacillus amyloliquefaciens subtilisin.
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公开(公告)号：EP0934402A1
公开(公告)日：1999-08-11
申请号：EP97910907.0
申请日：1997-10-07
发明人： BOWER, Benjamin, S. , CLARKSON, Kathleen, A. , COLLIER, Katherine, D. , KELLIS, James, T. , KELLY, Moira, B. , LARENAS, Edmund, A.
CPC分类号： C12N9/2437 , A23K20/189 , C11D3/38645 , D06M16/003 , D06M2101/06 , D06P5/02 , D06P5/158 , D21C5/005
摘要： A purified cellulase composition is provided which may be isolated from a fermentation culture of Trichoderma longibrachiatum and has a molecular weight of about 95-105 kD as approximated on SDS-PAGE, a pl of about 5.6-6.8 as estimated on an IEF gel and a pH optimum of about 5.0 on RBB-CMC when measured at 65 °C and pH4 or lower at temperatures of 40 °C and 50 °C.
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公开(公告)号：EP0885311A1
公开(公告)日：1998-12-23
申请号：EP97914869.0
申请日：1997-03-06
发明人： HSIEH, You-lo , HARTZELL, Mary, Michele , BOSTON, Matthew, G. , CLARKSON, Kathleen, A. , COLLIER, Katherine, D. , GRAYCAR, Thomas, P. , LARENAS, Edmund, A.
CPC分类号： D06M16/003 , D06M2101/06 , D06M2101/32 , D06M2200/00 , Y10S8/04
摘要： Textile fibers are treated with enzymes in the absence of surfactants, with the effect of increasing the wettability and absorbency of the fibers. The enzymes are pectinases, cellulases, proteases, lipases or combinations thereof. The wetting properties of cotton fibers are found to be most substantially improved by treatment with a mixture of cellulase and pectinase. The effects of five hydrolyzing enzymes on improving the hydrophilicity of several polyester fabrics have been studied. Four out of the five lipases studied improve the water wetting and absorbent properties of the regular polyester fabrics more than alkaline hydrolysis under optimal conditions (3N NaOH at 55 °C for 2 hours). Compared to aqueous hydrolysis, the enzyme reactions have shown to be effective under more moderate conditions, including a relatively low concentration (0.01 g/L), a shorter reaction time (10 minutes), at an ambient temperature (25 °C). Contrary to the results with alkaline hydrolysis, the improved water wettability is accompanied by full strength retention. Lipase has also shown to be effective in improving the wetting and absorbent properties of sulfonated polyester and microdenier polyester fabrics.
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8.发明公开METHOD AND COMPOSITIONS FOR TREATING CELLULOSE CONTAINING FABRICS USING TRUNCATED CELLULASE ENZYME COMPOSITIONS 失效法纤维素织物与简明纤维素酶ENZUME含组合物治疗
公开(公告)号：EP0807193A1
公开(公告)日：1997-11-19
申请号：EP96905208.0
申请日：1996-01-29
发明人： FOWLER, Timothy , CLARKSON, Kathleen, A. , WARD, Michael , COLLIER, Katherine, D. , LARENAS, Edmund
CPC分类号： D06P5/158 , A23K20/189 , C11D3/38645 , C12N9/2437 , C12N15/80 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , D06M16/003 , D06P5/02 , D06P5/137 , Y10T442/20
摘要： Improved methods of treating cellulose containing fabrics with cellulase comprising contacting the cellulose fabrics with truncated cellulase enzyme. Treatment of cellulose containing fabrics with cellulase core domains of the invention are disclosed as offering specific advantages of reduced redeposition of dye and increased abrasion.
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公开(公告)号：EP1025239B1
公开(公告)日：2008-01-23
申请号：EP98953936.6
申请日：1998-10-23
发明人： SCHELLENBERGER, Volker , KELLIS, James, T., Jr. , PAECH, Christian , NADHERNY, Joanne , NAKI, Donald, P. , POULOSE, Ayrookaran, J. , COLLIER, Katherine, D. , CALDWELL, Robert, M. , BAECK, André, C.
CPC分类号： C12N9/54 , A23G4/123 , A23K20/189 , A61K8/66 , A61K2800/86 , A61Q11/00 , A61Q19/00 , C11D3/386 , C11D3/38609 , C11D3/38618 , C11D3/3907 , C11D3/3945 , C12Y304/00 , C12Y304/21062
摘要： Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue correspond to positions 62, 212, 230, 232, 252 and 257 of Bacillus amyloliquefaciens subtilisin.
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公开(公告)号：EP1042501A2
公开(公告)日：2000-10-11
申请号：EP98966092.3
申请日：1998-12-23
发明人： SCHELLENBERGER, Volker , NAKI, Donald, P. , COLLIER, Katherine, D. , KELLIS, James, T., Jr. , NADHERNY, Joanne
IPC分类号： C12Q1/00
CPC分类号： C12Q1/00
摘要： An improved method for assaying the wash performance of new enzymes and/or new detergent formulations by comparing performance of enzyme cleaning effectiveness on washed soiled swatch cloths.
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