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公开(公告)号：EP1962959B1
公开(公告)日：2012-03-14
申请号：EP06830133.2
申请日：2006-11-27
发明人： CONDE-KNAPE, Karin , DANHO, Waleed , EHRLICH, George , FOTOUHI, Nader , FRY, David C. , KHAN, Wajiha , KONKAR, Anish , RONDINONE, Cristina Martha , SWISTOK, Joseph , TAUB, Rebecca Anne , TILLEY, Jefferson W.
IPC分类号： C07K14/575 , A61K38/10 , A61K38/00
CPC分类号： C07K14/57545 , A61K38/00 , A61K47/60
摘要： Provided herein are neuropeptide-2 receptor agonists of the formula (I): as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity and diabetes.
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公开(公告)号：EP2488195A2
公开(公告)日：2012-08-22
申请号：EP10770751.5
申请日：2010-10-08
发明人： CONDE-KNAPE, Karin , DANHO, Waleed , FOTOUHI, Nader , FRY, David, C. , KHAN, Wajiha , KONKAR, Anish , RONDINONE, Cristina, Martha , SWISTOK, Joseph , TILLEY, Jefferson, Wright
IPC分类号： A61K38/22
CPC分类号： C07K14/575 , A61K38/00 , C07K14/57545
摘要： Provided herein are neuropeptide-2 receptor agonists of the formula (I): as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity and diabetes.
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公开(公告)号：EP1962959A2
公开(公告)日：2008-09-03
申请号：EP06830133.2
申请日：2006-11-27
发明人： CONDE-KNAPE, Karin , DANHO, Waleed , EHRLICH, George , FOTOUHI, Nader , FRY, David C. , KHAN, Wajiha , KONKAR, Anish , RONDINONE, Cristina Martha , SWISTOK, Joseph , TAUB, Rebecca Anne , TILLEY, Jefferson W.
IPC分类号： A61P3/10
CPC分类号： C07K14/57545 , A61K38/00 , A61K47/60
摘要： Provided herein are neuropeptide-2 receptor agonists of the formula (I): as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity and diabetes.
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公开(公告)号：EP1844070A1
公开(公告)日：2007-10-17
申请号：EP06700451.5
申请日：2006-01-11
IPC分类号： C07K14/575 , A61K38/22 , C07K7/08
CPC分类号： C07K14/575 , A61K38/00 , C07K14/57545
摘要： The present invention refers to neuropeptide-2 receptor agonists of the formula (I): Y-R1-R2-X-R3-R4-R5-R6-R7-R8-R9-R10-R11-R12-R13-R14-NH2 (I); as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical composition's containing them, are useful for the treatment of diseases such as, for example, obesity.
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公开(公告)号：EP2632945A1
公开(公告)日：2013-09-04
申请号：EP11774034.0
申请日：2011-10-21
IPC分类号： C07K14/605 , A61P3/00
CPC分类号： C07K14/605 , A61K38/00 , A61K38/22
摘要： The present invention provides compounds which are analogs of glucose-dependent insulinotropic polypeptide (GIP) and pharmaceutically acceptable salts of such compounds. These compounds have activity as agonists of GIP receptor.
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公开(公告)号：EP1844070B1
公开(公告)日：2011-03-02
申请号：EP06700451.5
申请日：2006-01-11
IPC分类号： C07K14/575 , A61K38/22 , C07K7/08
CPC分类号： C07K14/575 , A61K38/00 , C07K14/57545
摘要： The present invention refers to neuropeptide-2 receptor agonists of the formula (I): Y-R1-R2-X-R3-R4-R5-R6-R7-R8-R9-R10-R11-R12-R13-R14-NH2 (I); as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical composition's containing them, are useful for the treatment of diseases such as, for example, obesity.
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