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    SYSTEMS AND METHODS FOR AUTOMATICALLY DISPLAYING PATTERNS IN BIOLOGICAL MONITORING DATA
    1.
    发明公开
    SYSTEMS AND METHODS FOR AUTOMATICALLY DISPLAYING PATTERNS IN BIOLOGICAL MONITORING DATA 审中-公开
    系统和方法可用于生物监测数据自动显示格局

    公开(公告)号：EP2649544A1

    公开(公告)日：2013-10-16

    申请号：EP11794044.5

    申请日：2011-12-06

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： BOUSAMRA, Steven ,  DUKE, David, L. ,  GALLEY, Paul, J. ,  MEARS, Mark ,  SONI, Abhishek, S.

    IPC分类号： G06F19/00

    CPC分类号： G16H50/70 ,  G06F19/00

    摘要： Systems and methods for automatically displaying patterns in biological data may include one or more processors, and machine readable instructions. The machine readable instructions can cause the one or more processors to divide biological data into segments of interest. The one or more processers can transform, automatically, each of the segments of interest into a set of features according to a mathematical algorithm. The one or more processers can cluster, automatically, the segments of interest into groups of clustered segments according to a clustering algorithm. The segments of interest can be grouped in the groups of clustered segments based at least in part upon the set of features. A cluster center can be associated with one of the groups of clustered segments. The one or more processers can present, automatically, the cluster center on a human machine interface.

    INSULIN OPTIMIZATION SYSTEMS AND TESTING METHODS WITH ADJUSTED EXIT CRITERION ACCOUNTING FOR SYSTEM NOISE ASSOCIATED WITH BIOMARKERS
    2.
    发明公开
    INSULIN OPTIMIZATION SYSTEMS AND TESTING METHODS WITH ADJUSTED EXIT CRITERION ACCOUNTING FOR SYSTEM NOISE ASSOCIATED WITH BIOMARKERS 审中-公开
    胰岛素优化系统，并与调整的拆除标准进行测试的程序，包括与生物标志物连接系统噪声

    公开(公告)号：EP2582297A1

    公开(公告)日：2013-04-24

    申请号：EP11730202.6

    申请日：2011-06-14

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： DUKE, David, L. ,  PERCIVAL, Matt ,  SONI, Abhishek S. ,  BOUSAMRA, Steven

    IPC分类号： A61B5/145 ,  G06F19/00

    CPC分类号： A61B5/14532 ,  G06F19/00 ,  G16H50/20

    摘要： Embodiments of a testing method for optimizing a therapy to a diabetic patient comprise collecting at least one sampling set of biomarker data, computing a probability distribution function, a hazard function, a risk function, and a risk value for the sampling set of biomarker data, wherein the probability distribution function is calculated to approximate the probability distribution of the biomarker data, the hazard function is a function which yields higher hazard values for biomarker readings in the sampling set indicative of higher risk of complications, the risk function is the product of the probability distribution function and the hazard function, and the risk value is calculated by the integral of the risk function, minimizing the risk value by adjusting the diabetic patient's therapy, and exiting the testing method when the risk value for at least one sampling set is minimized to an optimal risk level.

    MANAGEMENT METHOD AND SYSTEM FOR IMPLEMENTATION, EXECUTION, DATA COLLECTION, AND DATA ANALYSIS OF A STRUCTURED COLLECTION PROCEDURE WHICH RUNS ON A COLLECTION DEVICE
    5.
    发明公开
    MANAGEMENT METHOD AND SYSTEM FOR IMPLEMENTATION, EXECUTION, DATA COLLECTION, AND DATA ANALYSIS OF A STRUCTURED COLLECTION PROCEDURE WHICH RUNS ON A COLLECTION DEVICE 审中-公开
    履行，设计，数据收集和结构化集合进程的数据分析的收集设备，管理方法和系统

    公开(公告)号：EP2517133A1

    公开(公告)日：2012-10-31

    申请号：EP10803688.0

    申请日：2010-12-21

    申请人： Roche Diagnostics GmbH ,  F.Hoffmann-La Roche AG

    发明人： BOUSAMRA, Steven ,  SONI, Abhishek, S.

    IPC分类号： G06F19/00

    CPC分类号： A61B5/0002 ,  A61B5/05 ,  A61B5/14532 ,  A61B5/14546 ,  A61M31/00 ,  A61M2230/201 ,  C12Q1/006 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3456 ,  G16H10/20 ,  G16H10/40 ,  G16H20/17 ,  G16H80/00

    摘要： Embodiments of a testing method suitable for diabetic persons to optimize their administered insulin dosage comprise collecting one or more sampling sets of biomarker data, wherein each sampling set comprises a sufficient plurality of non-adverse sampling instances and wherein each sampling instance comprises an acceptable biomarker reading at a single point in time recorded upon compliance with adherence criteria, determining a biomarker sampling parameter from each sampling set, comparing the biomarker sampling parameter to a target biomarker range, calculating an insulin adjustment parameter associated with the biomarker sampling parameter if the biomarker sampling parameter falls outside the target biomarker range, adjusting the insulin dosage by the insulin adjustment parameter if the biomarker sampling parameter falls outside the target biomarker range and if the insulin dosage does not exceed maximum dosage, and exiting the testing method if the adjusted insulin dosage is optimized. The insulin dosage is optimized when one or more biomarker sampling parameters fall within a target biomarker range.

    摘要翻译： 适合于糖尿病人的测试方法的实施方案中，以优化其给药的胰岛素剂量包括收集一个或多个采样集的生物标志物的数据，worin每个采样集合包括非不利采样实例和worin每个取样实例的足够多的的可接受的生物标志读数包括 在记录在符合遵守标准的，确定性的采矿从每个采样集合的生物标记物采样参数，所述生物标志采样参数与靶生物标志物的范围，计算与所述生物标志采样参数相关的胰岛素调整参数在单个时间点，如果生物标志采样参数 如果靶生物标志物的范围之外，由所述胰岛素调整参数调整所述胰岛素剂量，如果生物标志采样参数，如果靶生物标志物的范围之外，并且如果胰岛素剂量的大小限制最大剂量，和离开测试方法如果调整胰岛素剂量是优化解 ZED。 所述胰岛素剂量被优化当一个或多个生物标志采样参数落在靶生物标志物的范围内。

    MANAGEMENT METHOD AND SYSTEM FOR IMPLEMENTATION, EXECUTION, DATA COLLECTION, AND DATA ANALYSIS OF A STRUCTURED COLLECTION PROCEDURE WHICH RUNS ON A COLLECTION DEVICE
    8.
    发明公开
    MANAGEMENT METHOD AND SYSTEM FOR IMPLEMENTATION, EXECUTION, DATA COLLECTION, AND DATA ANALYSIS OF A STRUCTURED COLLECTION PROCEDURE WHICH RUNS ON A COLLECTION DEVICE 审中-公开
    履行，设计，数据收集和结构化集合进程的数据分析的收集设备，管理方法和系统

    公开(公告)号：EP2382569A2

    公开(公告)日：2011-11-02

    申请号：EP09804010.8

    申请日：2009-12-21

    申请人： Roche Diagnostics GmbH ,  F. Hoffmann-La Roche AG

    发明人： SONI, Abhishek, S. ,  WEINERT, Stefan ,  RASCH-MENGES, Juergen ,  BOUSAMRA, Steven ,  WALLING, Paul, Douglas

    IPC分类号： G06F19/00

    CPC分类号： G06F17/30289 ,  G01N33/49 ,  G01N33/66 ,  G06F19/00 ,  G06F19/3418 ,  G16H10/20 ,  G16H40/63

    摘要： Embodiments related to a system and method managing the implementation, execution, data collection, and data analysis of a structured collection procedure running on a portable, hand-held collection device are disclosed. The collection device performing the structured collection procedure has program instructions that when executed by a processor causes the processor to initiate automatically a schedule of events of the structured collection procedure upon one or more entry criterions being met at some unknown time, store in memory patient data collected in accordance to the schedule of events, end automatically the structured collection procedure upon one or more exit criterions being met at some unknown time, and mark/indicate the structured collection procedure as completed if no exception occurred during performance of an event in the schedule of events.

    摘要翻译： 相关的系统和方法管理实现，执行，数据收集，和便携式，手持收集设备上运行的结构化收集程序的数据分析中游离缺失光盘的实施例。 执行结构化收集程序所述收集装置具有程序指令做当由处理器执行时致使所述处理器自动地开始在一个或多个进入准则的结构化收集过程的事件的时间表在某个未知时间被满足，存储在存储器中的患者数据 在雅舞蹈收集到的事件的时间表，结束时会自动在一个或多个退出准则的结构化收集规程正在遇到一些未知的时间，和标志/指示结构化收集程序已完成，如果在日程安排的活动进行期间没有发生任何异常 的事件。

    STRUCTURED TESTING METHOD FOR DIAGNOSTIC OR THERAPY SUPPORT OF A PATIENT WITH A CHRONIC DISEASE AND DEVICES THEREOF
    9.
    发明公开
    STRUCTURED TESTING METHOD FOR DIAGNOSTIC OR THERAPY SUPPORT OF A PATIENT WITH A CHRONIC DISEASE AND DEVICES THEREOF 审中-公开
    结构化测试程序用于诊断或治疗支持与慢性疾病和DEVICES为此的患者

    公开(公告)号：EP2382568A2

    公开(公告)日：2011-11-02

    申请号：EP09803731.0

    申请日：2009-12-21

    申请人： Roche Diagnostics GmbH ,  F. Hoffmann-La Roche AG

    发明人： WALLING, P., Douglas ,  SONI, Abhishek, S. ,  RASCH-MENGES, Juergen ,  WEINERT, Stefan ,  BOUSAMRA, Steven ,  EISENHARDT, Christoph

    IPC分类号： G06F19/00

    CPC分类号： G06F17/30289 ,  G01N33/49 ,  G01N33/66 ,  G06F19/00 ,  G06F19/3418 ,  G16H10/20 ,  G16H40/63

    摘要： Embodiments related to a system and method managing the implementation, execution, data collection, and data analysis of a structured collection procedure running on a portable, hand-held collection device are disclosed. The collection device performing the structured collection procedure has program instructions that when executed by a processor causes the processor to initiate automatically a schedule of events of the structured collection procedure upon one or more entry criterions being met at some unknown time, store in memory patient data collected in accordance to the schedule of events, end automatically the structured collection procedure upon one or more exit criterions being met at some unknown time, and mark/indicate the structured collection procedure as completed if no exception occurred during performance of an event in the schedule of events.

    摘要翻译： 相关的系统和方法管理实现，执行，数据收集，和便携式，手持收集设备上运行的结构化收集程序的数据分析中游离缺失光盘的实施例。 执行结构化收集程序所述收集装置具有程序指令做当由处理器执行时致使所述处理器自动地开始在一个或多个进入准则的结构化收集过程的事件的时间表在某个未知时间被满足，存储在存储器中的患者数据 在雅舞蹈收集到的事件的时间表，结束时会自动在一个或多个退出准则的结构化收集规程正在遇到一些未知的时间，和标志/指示结构化收集程序已完成，如果在日程安排的活动进行期间没有发生任何异常 的事件。