公开(公告)号：EP1197496B1

公开(公告)日：2007-07-11

申请号：EP00946453.8

申请日：2000-07-24

申请人： Kangawa, Kenji

发明人： KANGAWA, Kenji ,  KOJIMA, Masayasu ,  HOSODA, Hiroshi, Towa Minoo Homes A808 ,  MATSUO, Hisayuki ,  MINAMITAKE, Yoshiharu

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K14/46 ,  C07K14/465 ,  C07K14/575 ,  C07K16/18 ,  C12P21/02 ,  A61K38/18 ,  A61P5/06 ,  A61P19/08

CPC分类号： C07K14/575 ,  A01K2217/05 ,  A61K9/0019 ,  A61K38/00 ,  A61K47/42 ,  A61K48/00 ,  C07K14/461 ,  C07K14/463 ,  C07K14/465 ,  C07K14/47 ,  C07K14/4702

摘要： The present invention provides a novel peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof.

公开(公告)号：EP1197496B8

公开(公告)日：2007-10-03

申请号：EP00946453.8

申请日：2000-07-24

申请人： Kangawa, Kenji

发明人： KANGAWA, Kenji ,  KOJIMA, Masayasu ,  HOSODA, Hiroshi ,  MATSUO, Hisayuki ,  MINAMITAKE, Yoshiharu c/o Asubio Pharma Co., Ltd.,

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K14/46 ,  C07K14/465 ,  C07K14/575 ,  C07K16/18 ,  C12P21/02 ,  A61K38/18 ,  A61P5/06 ,  A61P19/08

CPC分类号： C07K14/575 ,  A01K2217/05 ,  A61K9/0019 ,  A61K38/00 ,  A61K47/42 ,  A61K48/00 ,  C07K14/461 ,  C07K14/463 ,  C07K14/465 ,  C07K14/47 ,  C07K14/4702

摘要： The present invention provides a novel peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof.

公开(公告)号：EP1197496A1

公开(公告)日：2002-04-17

申请号：EP00946453.8

申请日：2000-07-24

申请人： Kangawa, Kenji

发明人： KANGAWA, Kenji ,  KOJIMA, Masayasu ,  HOSODA, Hiroshi, Towa Minoo Homes A808 ,  MATSUO, Hisayuki ,  MINAMITAKE, Y., Suntory Inst. for Med. Res.& Dev.

IPC分类号： C07K14/47 ,  C12N15/12 ,  C12N1/21 ,  C12P21/02 ,  C07K16/18 ,  A61K38/18 ,  A61P5/06 ,  A61P19/08 ,  A61K45/00 ,  A61K48/00 ,  G01N33/53

CPC分类号： C07K14/575 ,  A01K2217/05 ,  A61K9/0019 ,  A61K38/00 ,  A61K47/42 ,  A61K48/00 ,  C07K14/461 ,  C07K14/463 ,  C07K14/465 ,  C07K14/47 ,  C07K14/4702

摘要： The present invention provides a novel peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof.

摘要翻译： 本发明提供诱导生长激素分泌的具有增加细胞内钙离子浓度的活性的新型肽类化合物，其中至少一个氨基酸被修饰的氨基酸和/或非氨基酸置换 化合物或其药学上可接受的盐。