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公开(公告)号:EP2029626A4
公开(公告)日:2010-07-21
申请号:EP07797900
申请日:2007-05-31
申请人: LPATH INC
CPC分类号: G01N33/92 , A61K47/544 , A61K47/60 , A61K47/643 , A61K47/646 , A61K2039/505 , C07K16/18 , C07K16/30 , C07K2317/24 , C07K2317/56 , C07K2317/73 , C07K2317/74
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公开(公告)号:EP2820414A4
公开(公告)日:2015-08-05
申请号:EP13754278
申请日:2013-02-27
申请人: LPATH INC
发明人: SABBADINI ROGER A
CPC分类号: G01N33/92 , G01N33/6896 , G01N2405/04 , G01N2800/2871
摘要: Methods and kits for detecting and diagnosing neurotrauma (e.g., traumatic brain injury, stroke, or spinal cord injury) are provided. These methods rely on the determination of lysophosphatidic acid (LPA) and/or LPA metabolite levels in patient samples following suspected injury.
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公开(公告)号:EP2164992A4
公开(公告)日:2013-05-01
申请号:EP08756421
申请日:2008-05-29
申请人: LPATH INC
CPC分类号: G01N33/92 , A61K2039/505 , C07K16/3076 , C07K16/44 , C07K2317/24 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/54386 , G01N33/577 , G01N2405/04
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公开(公告)号:EP2374001A4
公开(公告)日:2013-03-13
申请号:EP09831241
申请日:2009-12-04
申请人: LPATH INC
IPC分类号: A61K39/395 , C07K16/18
CPC分类号: C07K16/18 , A61K39/39591 , A61K2039/505 , C07K2299/00 , C07K2317/24 , C07K2317/55 , C07K2317/565 , C07K2317/92
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公开(公告)号:EP2741756A4
公开(公告)日:2015-04-22
申请号:EP12822440
申请日:2012-08-09
申请人: LPATH INC
发明人: SABBADINI ROGER A
IPC分类号: A61K35/48 , A61K35/28 , A61K35/30 , A61K35/34 , A61K35/39 , A61P43/00 , C07K16/44 , C12N5/071 , A61K35/35 , A61K35/545
CPC分类号: A61K39/39533 , A61K35/28 , A61K35/30 , A61K35/34 , A61K35/35 , A61K35/39 , A61K35/545 , A61K2039/505 , C07K16/18 , C07K16/44 , C07K2317/24 , C07K2317/76 , C12N5/0602 , C12N5/0623 , C12N2500/36
摘要: Methods are provided for stem cell therapy using inhibitors of lysophosphatidic acid (LPA). Inhibition of LPA may be direct or indirect; particularly preferred direct inhibitors of LPA are antibodies to LPA, including humanized monoclonal antibodies to LPA. Such inhibitors are used in combination with stem cells for the treatment of injuries, diseases, or conditions amenable to treatment by stem cell therapy.
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6.HUMANIZED ANTIBODY COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID 审中-公开
标题翻译: 人源化抗体组合物和方法溶血磷脂绑定机制公开(公告)号:EP2419446A4
公开(公告)日:2013-01-23
申请号:EP10765230
申请日:2010-04-16
申请人: LPATH INC
发明人: SABBADINI ROGER A , GARLAND WILLIAM A , HANSEN GENEVIEVE , JONES STEVEN TARRAN , WILLIAMS DAVID GARETH
IPC分类号: C07K16/18
CPC分类号: C07K16/18 , A61K2039/505 , C07K16/44 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/70 , C07K2317/73 , C07K2317/76 , C07K2317/92
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7.COMPOSITIONS AND METHODS FOR BINDING SPHINGOSINE-1-PHOSPHATE 有权
标题翻译: ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BINDUNG VON SPHINGOSIN-1-PHOSPHAT公开(公告)号:EP2087002A4
公开(公告)日:2010-06-30
申请号:EP07871262
申请日:2007-10-26
申请人: LPATH INC
发明人: SABBADINI ROGER A , GARLAND WILLIAM A , HANSEN GENEVIEVE , JONES STEVEN TARRAN , WILLIAMS DAVID GARETH
IPC分类号: C07K16/00 , A61K39/395 , C07H21/04 , C07K16/18 , C07K16/38 , C12N5/10 , C12N5/12 , C12N15/00 , C12P21/08 , G01N33/53
CPC分类号: C07K16/44 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565
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8.METHODS AND REAGENTS FOR DETECTING BIOACTIVE LIPIDS 有权
标题翻译: VERFAHREN UND REENENENEN ZUM NACHWEIS BIOLOGISCH AKTIVER LIPIDE公开(公告)号:EP2027142A4
公开(公告)日:2009-08-19
申请号:EP07797899
申请日:2007-05-31
申请人: LPATH INC
CPC分类号: G01N33/92 , A61K2039/505 , C07K16/18 , C07K16/30 , C07K2317/24 , C07K2317/56 , C07K2317/73 , G01N33/6854
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9.
公开(公告)号:EP2083862A4
公开(公告)日:2012-09-19
申请号:EP07863554
申请日:2007-10-26
申请人: LPATH INC
IPC分类号: A61K39/395 , A61P27/02 , C07K16/00 , C12P21/08
CPC分类号: A61K38/08 , A61K38/10 , A61K2039/505 , C07K16/18 , C07K2317/24 , C07K2317/56 , C07K2317/92
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10.
公开(公告)号:EP2155239A4
公开(公告)日:2011-05-04
申请号:EP08745187
申请日:2008-04-05
申请人: LPATH INC
发明人: SABBADINI ROGER A
IPC分类号: A61K39/00 , A61K39/395 , C07K16/18 , C07K16/30
CPC分类号: C07K16/3076 , A61K39/39591 , C07K16/18 , C07K2317/73 , C07K2317/74 , C07K2317/76
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