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公开(公告)号：EP2546331B1
公开(公告)日：2019-07-03
申请号：EP11753297.8
申请日：2011-03-04
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2.发明授权ISOPROPYL ALCOHOL-PRODUCING BACTERIUM HAVING IMPROVED PRODUCTIVITY BY GNTR DESTRUCTION 有权通过GNTR杀灭提高生产力的异丙醇酒生产细菌
公开(公告)号：EP2604683B1
公开(公告)日：2018-02-28
申请号：EP11816495.3
申请日：2011-08-11
发明人： AMANO, Koh , SHIRAI, Tomokazu , TAKAHASHI, Hitoshi , HIRANO, Junichiro , MATSUMOTO, Yoshiko , TAKEBAYASHI, Nozomi , WADA, Mitsufumi , SHIMIZU, Hiroshi , FURUSAWA, Chikara , HIRASAWA, Takashi
CPC分类号： C12P7/04 , C07C1/24 , C07C45/002 , C07C2529/70 , C07K14/245 , C12N9/0006 , C12N9/88 , C12N15/70 , C12P7/28 , Y02P20/52 , C07C11/06 , C07C49/08
摘要： An isopropyl alcohol-producing Escherichia coli includes an isopropyl alcohol production system, wherein an activity of transcriptional repressor GntR is inactivated, and the isopropyl alcohol-producing Escherichia coli preferably further includes a group of auxiliary enzymes having an enzyme activity expression pattern with which isopropyl alcohol production capacity achieved by the inactivation of the GntR activity is maintained or enhanced. A method of producing isopropyl alcohol includes producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli. A method of producing acetone includes contacting the isopropyl alcohol obtained by the isopropyl alcohol production method with a complex oxide that includes zinc oxide and at least one oxide containing a Group 4 element, and that is prepared by coprecipitation. A method of producing propylene includes contacting isopropyl alcohol and acetone obtained by the production method with a solid acidic substance and a Cu-containing hydrogenation catalyst as catalysts.
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3.发明公开ISOPROPYL ALCOHOL-PRODUCING BACTERIUM HAVING IMPROVED PRODUCTIVITY BY GNTR DESTRUCTION 有权上生产力的提高GNTR销毁异丙基制造细菌
公开(公告)号：EP2604683A1
公开(公告)日：2013-06-19
申请号：EP11816495.3
申请日：2011-08-11
发明人： AMANO, Koh , SHIRAI, Tomokazu , TAKAHASHI, Hitoshi , HIRANO, Junichiro , MATSUMOTO, Yoshiko , TAKEBAYASHI, Nozomi , WADA, Mitsufumi , SHIMIZU, Hiroshi , FURUSAWA, Chikara , HIRASAWA, Takashi
CPC分类号： C12P7/04 , C07C1/24 , C07C45/002 , C07C2529/70 , C07K14/245 , C12N9/0006 , C12N9/88 , C12N15/70 , C12P7/28 , Y02P20/52 , C07C11/06 , C07C49/08
摘要： An isopropyl alcohol-producing Escherichia coli includes an isopropyl alcohol production system, wherein an activity of transcriptional repressor GntR is inactivated, and the isopropyl alcohol-producing Escherichia coli preferably further includes a group of auxiliary enzymes having an enzyme activity expression pattern with which isopropyl alcohol production capacity achieved by the inactivation of the GntR activity is maintained or enhanced. A method of producing isopropyl alcohol includes producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli. A method of producing acetone includes contacting the isopropyl alcohol obtained by the isopropyl alcohol production method with a complex oxide that includes zinc oxide and at least one oxide containing a Group 4 element, and that is prepared by coprecipitation. A method of producing propylene includes contacting isopropyl alcohol and acetone obtained by the production method with a solid acidic substance and a Cu-containing hydrogenation catalyst as catalysts.
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公开(公告)号：EP2546331A1
公开(公告)日：2013-01-16
申请号：EP11753297.8
申请日：2011-03-04
发明人： MATSUMOTO, Yoshiko , HIRANO, Junichiro , MORISHIGE, Takashi , SHIRAI, Tomokazu , TAKAHASHI, Hitoshi , AMANO, Koh , TAKEBAYASHI, Nozomi , WADA, Mitsufumi , SHIMIZU, Hiroshi , FURUSAWA, Chikara , HIRASAWA, Takashi
CPC分类号： C12P7/04 , C12N9/0006 , C12N9/0036 , C12N9/1029 , C12N15/70
摘要： An isopropyl alcohol-producing Escherichia coli equipped with an isopropyl alcohol production system, having at least one enhanced enzyme activity selected from the group consisting of an enhanced malate dehydrogenase, activity, an enhanced NAD(P) + transhydrogenase (AB-specific) activity, and an enhanced thiolase activity, and an isopropyl alcohol producing method including producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli,
摘要翻译： 具有选自增强的苹果酸脱氢酶，活性，增强的NAD（P）+转氢酶（AB特异性）活性，增强的苹果酸脱氢酶活性，至少一种增强的酶活性的异丙醇生产系统的异丙醇生产大肠杆菌 提高的硫解酶活性，以及异丙醇生产方法，包括使用产生异丙醇的大肠杆菌从植物来源的原料生产异丙醇，
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5.发明公开ISOPROPYL ALCOHOL-PRODUCING BACTERIUM AND METHOD OF PRODUCING ISOPROPYL ALCOHOL USING THE SAME 审中-公开异丙制造细菌及其制造方法ISOPROPYL使用其
公开(公告)号：EP2184354A1
公开(公告)日：2010-05-12
申请号：EP08790886.9
申请日：2008-07-04
发明人： TAKEBAYASHI, Nozomi , WADA, Mitsufumi , MOCHIZUKI, Daisuke , YOSHIMI, Fuminobu , WATANABE, Seiichi , TAKAHASHI, Hitoshi , MORISHIGE, Takashi
CPC分类号： C12P7/04 , C12M21/12 , C12M47/10 , C12M47/20 , C12N9/0006 , C12N9/1029 , C12N9/13 , C12N9/88
摘要： The invention provides: an isopropyl alcohol-producing bacterium which has an acetoacetate decarboxylase activity, an isopropyl alcohol dehydrogenase activity, a CoA transferase activity and a thiolase activity having been imparted thereto and is capable of producing isopropyl alcohol from a plant-derived material; a method of producing isopropyl alcohol whereby isopropyl alcohol is produced from a plant-derived material by using this isopropyl alcohol-producing bacterium; and an apparatus therefor.
摘要翻译： 本发明提供了：以异丙醇生产细菌，其具有乙酰乙酸脱羧酶活性，异丙醇脱氢酶活性，CoA转移酶活性及硫解酶活性已经被赋予于此，并且能够产生由植物来源的材料的异丙醇; 生产异丙醇由此异丙醇是从植物来源的材料，通过使用本异丙醇生产细菌产生的方法; 和设备为此。
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6.发明授权
公开(公告)号：EP2184354B1
公开(公告)日：2018-08-22
申请号：EP08790886.9
申请日：2008-07-04
发明人： TAKEBAYASHI, Nozomi , WADA, Mitsufumi , MOCHIZUKI, Daisuke , YOSHIMI, Fuminobu , WATANABE, Seiichi , TAKAHASHI, Hitoshi , MORISHIGE, Takashi
CPC分类号： C12P7/04 , C12M21/12 , C12M47/10 , C12M47/20 , C12N9/0006 , C12N9/1029 , C12N9/13 , C12N9/88
摘要： The invention provides: an isopropyl alcohol-producing bacterium which has an acetoacetate decarboxylase activity, an isopropyl alcohol dehydrogenase activity, a CoA transferase activity and a thiolase activity having been imparted thereto and is capable of producing isopropyl alcohol from a plant-derived material; a method of producing isopropyl alcohol whereby isopropyl alcohol is produced from a plant-derived material by using this isopropyl alcohol-producing bacterium; and an apparatus therefor.
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7.发明授权ISOPROPYL ALCOHOL-PRODUCING BACTERIUM AND METHOD FOR PRODUCING ISOPROPYL ALCOHOL 有权异丙醇生产细菌和生产异丙醇的方法
公开(公告)号：EP2479255B1
公开(公告)日：2015-03-04
申请号：EP10817144.8
申请日：2010-09-13
CPC分类号： C12N9/88 , C12N9/0008 , C12N9/1029 , C12P7/04 , C12Y203/01016 , C12Y401/01004
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公开(公告)号：EP2738247A1
公开(公告)日：2014-06-04
申请号：EP12819719.1
申请日：2012-07-27
发明人： FUJII, Ryota , SHIRAI, Tomokazu , ARAKI, Tadashi , AMANO, Koh , MATSUMOTO, Yoshiko , TATENO, Toshihiro , TAKEBAYASHI, Nozomi , MORISHIGE, Takashi , TAKAHASHI, Hitoshi , WADA, Mitsufumi , SHIMIZU, Hiroshi , FURUSAWA, Chikara , HIRASAWA, Takashi , HIDESAKI, Tomonori , ENDO, Ayako , JÜRGEN-LOHMANN, Dominik Lukas , MADHAVAN, Anjali , CHONG, SU SUN
CPC分类号： C12P19/40 , C12N1/20 , C12N9/0006 , C12N9/88 , C12N9/93 , C12P7/04 , C12P7/28 , C12P13/14 , C12P19/32 , C12Y101/0106 , C12Y101/01081 , C12Y401/01047 , C12Y401/03024 , C12Y602/01009
摘要： An acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same are provided. An acetyl-CoA-producing microorganism including an acetyl-CoA production cycle obtained by imparting at least one type of enzymatic activity selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase, and hydroxypyruvate reductase, to a microorganism.
摘要翻译： 提供了能够使用二氧化碳有效地合成乙酰辅酶A的乙酰辅酶A生产微生物和使用其的物质制备方法。 一种乙酰辅酶A生产微生物，其包括通过赋予选自苹果酸硫激酶，苹果酰辅酶A裂解酶，乙醛酸卡巴肼，2-羟基-3-氧代丙酸酯还原酶中的至少一种酶活性而获得的乙酰辅酶A生产循环， 和羟丙酮酸还原酶。
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9.发明公开ISOPROPYL ALCOHOL-PRODUCING BACTERIUM AND METHOD FOR PRODUCING ISOPROPYL ALCOHOL 有权异丙基丙烯酸脂肪酸巴西维他命ZUR HERSTELLUNG VON ISOPROPYLALKOHOL
公开(公告)号：EP2479255A1
公开(公告)日：2012-07-25
申请号：EP10817144.8
申请日：2010-09-13
CPC分类号： C12N9/88 , C12N9/0008 , C12N9/1029 , C12P7/04 , C12Y203/01016 , C12Y401/01004
摘要： The present invention provides an isopropyl alcohol-producing Escherichia coli that includes at least a sucrose hydrolase gene that belongs to a sucrose non-PTS gene group, and an imparted or enhanced isopropyl alcohol production system, and an isopropyl alcohol production method of producing isopropyl alcohol from a sucrose-containing plant-derived raw material using the isopropyl alcohol-producing Escherichia coil .
摘要翻译： 本发明提供一种产生异丙醇的大肠杆菌，其至少包含属于蔗糖非PTS基因组的蔗糖水解酶基因，以及赋予或增强的异丙醇生产系统和产生异丙醇的异丙醇生产方法 来自含蔗糖的植物来源的原料，使用产生异丙醇的大肠杆菌。
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