公开(公告)号：EP2604683B1

公开(公告)日：2018-02-28

申请号：EP11816495.3

申请日：2011-08-11

申请人： Mitsui Chemicals, Inc.

发明人： AMANO, Koh ,  SHIRAI, Tomokazu ,  TAKAHASHI, Hitoshi ,  HIRANO, Junichiro ,  MATSUMOTO, Yoshiko ,  TAKEBAYASHI, Nozomi ,  WADA, Mitsufumi ,  SHIMIZU, Hiroshi ,  FURUSAWA, Chikara ,  HIRASAWA, Takashi

IPC分类号： C12N1/21 ,  C12N15/09 ,  C12P7/04

CPC分类号： C12P7/04 ,  C07C1/24 ,  C07C45/002 ,  C07C2529/70 ,  C07K14/245 ,  C12N9/0006 ,  C12N9/88 ,  C12N15/70 ,  C12P7/28 ,  Y02P20/52 ,  C07C11/06 ,  C07C49/08

摘要： An isopropyl alcohol-producing Escherichia coli includes an isopropyl alcohol production system, wherein an activity of transcriptional repressor GntR is inactivated, and the isopropyl alcohol-producing Escherichia coli preferably further includes a group of auxiliary enzymes having an enzyme activity expression pattern with which isopropyl alcohol production capacity achieved by the inactivation of the GntR activity is maintained or enhanced. A method of producing isopropyl alcohol includes producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli. A method of producing acetone includes contacting the isopropyl alcohol obtained by the isopropyl alcohol production method with a complex oxide that includes zinc oxide and at least one oxide containing a Group 4 element, and that is prepared by coprecipitation. A method of producing propylene includes contacting isopropyl alcohol and acetone obtained by the production method with a solid acidic substance and a Cu-containing hydrogenation catalyst as catalysts.

公开(公告)号：EP2546331B1

公开(公告)日：2019-07-03

申请号：EP11753297.8

申请日：2011-03-04

申请人： Mitsui Chemicals, Inc.

发明人： MATSUMOTO, Yoshiko ,  HIRANO, Junichiro ,  MORISHIGE, Takashi ,  SHIRAI, Tomokazu ,  TAKAHASHI, Hitoshi ,  AMANO, Koh ,  TAKEBAYASHI, Nozomi ,  WADA, Mitsufumi ,  SHIMIZU, Hiroshi ,  FURUSAWA, Chikara ,  HIRASAWA, Takashi

IPC分类号： C12N1/21 ,  C12P7/04 ,  C12N15/09

公开(公告)号：EP2604683A1

公开(公告)日：2013-06-19

申请号：EP11816495.3

申请日：2011-08-11

申请人： Mitsui Chemicals, Inc.

发明人： AMANO, Koh ,  SHIRAI, Tomokazu ,  TAKAHASHI, Hitoshi ,  HIRANO, Junichiro ,  MATSUMOTO, Yoshiko ,  TAKEBAYASHI, Nozomi ,  WADA, Mitsufumi ,  SHIMIZU, Hiroshi ,  FURUSAWA, Chikara ,  HIRASAWA, Takashi

IPC分类号： C12N1/21 ,  C12N15/09 ,  C12P7/04

CPC分类号： C12P7/04 ,  C07C1/24 ,  C07C45/002 ,  C07C2529/70 ,  C07K14/245 ,  C12N9/0006 ,  C12N9/88 ,  C12N15/70 ,  C12P7/28 ,  Y02P20/52 ,  C07C11/06 ,  C07C49/08

摘要： An isopropyl alcohol-producing Escherichia coli includes an isopropyl alcohol production system, wherein an activity of transcriptional repressor GntR is inactivated, and the isopropyl alcohol-producing Escherichia coli preferably further includes a group of auxiliary enzymes having an enzyme activity expression pattern with which isopropyl alcohol production capacity achieved by the inactivation of the GntR activity is maintained or enhanced. A method of producing isopropyl alcohol includes producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli. A method of producing acetone includes contacting the isopropyl alcohol obtained by the isopropyl alcohol production method with a complex oxide that includes zinc oxide and at least one oxide containing a Group 4 element, and that is prepared by coprecipitation. A method of producing propylene includes contacting isopropyl alcohol and acetone obtained by the production method with a solid acidic substance and a Cu-containing hydrogenation catalyst as catalysts.

公开(公告)号：EP2546331A1

公开(公告)日：2013-01-16

申请号：EP11753297.8

申请日：2011-03-04

申请人： Mitsui Chemicals, Inc.

发明人： MATSUMOTO, Yoshiko ,  HIRANO, Junichiro ,  MORISHIGE, Takashi ,  SHIRAI, Tomokazu ,  TAKAHASHI, Hitoshi ,  AMANO, Koh ,  TAKEBAYASHI, Nozomi ,  WADA, Mitsufumi ,  SHIMIZU, Hiroshi ,  FURUSAWA, Chikara ,  HIRASAWA, Takashi

IPC分类号： C12N1/21 ,  C12P7/04 ,  C12N15/09

CPC分类号： C12P7/04 ,  C12N9/0006 ,  C12N9/0036 ,  C12N9/1029 ,  C12N15/70

摘要： An isopropyl alcohol-producing Escherichia coli equipped with an isopropyl alcohol production system, having at least one enhanced enzyme activity selected from the group consisting of an enhanced malate dehydrogenase, activity, an enhanced NAD(P) + transhydrogenase (AB-specific) activity, and an enhanced thiolase activity, and an isopropyl alcohol producing method including producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli,

摘要翻译： 具有选自增强的苹果酸脱氢酶，活性，增强的NAD（P）+转氢酶（AB特异性）活性，增强的苹果酸脱氢酶活性，至少一种增强的酶活性的异丙醇生产系统的异丙醇生产大肠杆菌 提高的硫解酶活性，以及​​异丙醇生产方法，包括使用产生异丙醇的大肠杆菌从植物来源的原料生产异丙醇，

公开(公告)号：EP2738247A1

公开(公告)日：2014-06-04

申请号：EP12819719.1

申请日：2012-07-27

申请人： Mitsui Chemicals, Inc.

发明人： FUJII, Ryota ,  SHIRAI, Tomokazu ,  ARAKI, Tadashi ,  AMANO, Koh ,  MATSUMOTO, Yoshiko ,  TATENO, Toshihiro ,  TAKEBAYASHI, Nozomi ,  MORISHIGE, Takashi ,  TAKAHASHI, Hitoshi ,  WADA, Mitsufumi ,  SHIMIZU, Hiroshi ,  FURUSAWA, Chikara ,  HIRASAWA, Takashi ,  HIDESAKI, Tomonori ,  ENDO, Ayako ,  JÜRGEN-LOHMANN, Dominik Lukas ,  MADHAVAN, Anjali ,  CHONG, SU SUN

IPC分类号： C12N1/21 ,  C12P7/04 ,  C12P7/28 ,  C12P19/32 ,  C12N15/09

CPC分类号： C12P19/40 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/88 ,  C12N9/93 ,  C12P7/04 ,  C12P7/28 ,  C12P13/14 ,  C12P19/32 ,  C12Y101/0106 ,  C12Y101/01081 ,  C12Y401/01047 ,  C12Y401/03024 ,  C12Y602/01009

摘要： An acetyl-CoA-producing microorganism, which is capable of efficiently synthesizing acetyl-CoA using carbon dioxide, and a substance production method using the same are provided. An acetyl-CoA-producing microorganism including an acetyl-CoA production cycle obtained by imparting at least one type of enzymatic activity selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase, and hydroxypyruvate reductase, to a microorganism.

摘要翻译： 提供了能够使用二氧化碳有效地合成乙酰辅酶A的乙酰辅酶A生产微生物和使用其的物质制备方法。 一种乙酰辅酶A生产微生物，其包括通过赋予选自苹果酸硫激酶，苹果酰辅酶A裂解酶，乙醛酸卡巴肼，2-羟基-3-氧代丙酸酯还原酶中的至少一种酶活性而获得的乙酰辅酶A生产循环， 和羟丙酮酸还原酶。