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公开(公告)号：EP3604526A1
公开(公告)日：2020-02-05
申请号：EP18777395.7
申请日：2018-03-15
摘要： A polypeptide includes, in the amino acid sequence of SEQ ID NO: 1 or a similar sequence, at least one specific amino acid substitution on at least one of the 14th, 37th, 209th, 293rd, and 319th amino acid residues from the N-terminal of the amino acid sequence of SEQ ID NO: 1. A polynucleotide, an expression cassette, a vector, and a transformant include a base sequence encoding the amino acid sequence of the polypeptide. A method of producing the polypeptide and a method of producing 2-deoxy-scyllo-inosose are also provided.
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公开(公告)号：EP2546331B1
公开(公告)日：2019-07-03
申请号：EP11753297.8
申请日：2011-03-04
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公开(公告)号：EP1669460B1
公开(公告)日：2016-12-21
申请号：EP04773417.3
申请日：2004-09-17
发明人： WADA, Mitsufumi , OIKAWA, Toshihiro , MOCHIZUKI, Daisuke , TOKUDA, Junko , KAWASHIMA, Miyuki , ARAKI, Tadashi , ABE, Reiko , MIYAKE, Hitoki , TAKAHASHI, Hitoshi , SAWAI, Hideki , MIMITSUKA, Takashi , MORISHIGE, Takashi , HIGASHI, Yosuke
CPC分类号： C12P7/56
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4.发明授权BACTERIUM CAPABLE OF PRODUCING 2-DEOXY-SCYLLO-INOSOSE (DOI), AND PROCESS FOR PRODUCING 2-DEOXY-SCYLLO-INOSOSE (DOI) BY USING SAME 有权WITH能力生产的2-脱氧 - 青蟹肌糖（DOI），及其工艺利用细菌生产2-脱氧 - 青蟹肌糖（DOI）
公开(公告)号：EP2371952B1
公开(公告)日：2016-07-27
申请号：EP09824752.1
申请日：2009-10-30
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公开(公告)号：EP2025760B1
公开(公告)日：2013-06-05
申请号：EP07737127.6
申请日：2007-04-27
CPC分类号： C12P7/42 , C12N9/0006 , C12N9/0036
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6.发明公开BACTERIUM CAPABLE OF PRODUCING 2-DEOXY-SCYLLO-INOSOSE (DOI), AND PROCESS FOR PRODUCING 2-DEOXY-SCYLLO-INOSOSE (DOI) BY USING SAME 有权WITH能力生产的2-脱氧 - 青蟹肌糖（DOI），及其工艺利用细菌生产2-脱氧 - 青蟹肌糖（DOI）
公开(公告)号：EP2371952A1
公开(公告)日：2011-10-05
申请号：EP09824752.1
申请日：2009-10-30
发明人： TOKUDA, Junko , NATSUJI, Tomoyuki , TAKAHASHI, Hitoshi , ARAKI, Tadashi , MORISHIGE, Takashi , TAKAHASHI, Katsuyuki , WADA, Mitsufumi
摘要： Disclosed is an Escherichia coli producing 2-deoxy- scyllo -inosose (DOI), which, from a sucrose non-PTS gene group, has at least a sucrose hydrolase (CscA)-encoding gene and which is provided with a DOI production system or has an enhanced DOI production system. The Escherichia coli preferably further includes a system to enhance sugar uptake capacity. There is also disclosed a method of producing DOI from a plant-derived raw material containing sucrose by using the Escherichia coli.
摘要翻译： 公开是大肠杆菌生产2-脱氧 - 青蟹-inosose（DOI），其中，从蔗糖非PTS基因组，具有至少设置有一个DOI生产系统中的蔗糖水解酶（CSCA）编码基因和所有或 具有增强的DOI生产系统，该大肠杆菌优选地进一步包括一个系统，以提高糖摄取能力。 因此，存在来自植物来源的原料，通过使用大肠杆菌含有蔗糖产游离缺失DOI的方法的盘。
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7.发明授权METHOD FOR PRODUCING LACTIC ACID FROM PLANT-DERIVED RAW MATERIAL, AND LACTIC-ACID-PRODUCING BACTERIUM 有权从植物来源的原料生产乳酸的方法和产酸乳酸的细菌
公开(公告)号：EP2336295B1
公开(公告)日：2018-01-24
申请号：EP09814543.6
申请日：2009-09-11
发明人： MORISHIGE, Takashi , TAKAHASHI, Katsuyuki , TAKAHASHI, Hitoshi , WADA, Mitsufumi , MOCHIZUKI, Daisuke , MIYAZAWA, Daisuke , ARAKI, Tadashi
CPC分类号： C12P7/56 , C12N1/20 , C12N9/1205 , C12N9/2451
摘要： The present invention provides: a lactic acid-producing Escherichia coli comprising at least one gene of a sucrose non-PTS gene group, including at least a sucrose hydrolase gene, provided that a combination of a repressor protein (cscR), a sucrose hydrolase (cscA), a fructokinase (cscK) and a sucrose permease (cscB) and a combination of a sucrose hydrolase (cscA), a fructokinase (cscK) and a sucrose permease (cscB) are excluded, wherein the lactic acid-producing Escherichia coli comprises a lactic acid production enhancing system provided by genetic recombination; and a lactic acid production method including producing lactic acid from a plant-derived sucrose-containing raw material by using the lactic acid-producing Escherichia coli.
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8.发明授权
公开(公告)号：EP2025759B1
公开(公告)日：2017-06-07
申请号：EP07737126.8
申请日：2007-04-27
CPC分类号： C12N9/1077 , C12P7/42 , C12Y204/02011
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9.发明公开ISOPROPYL ALCOHOL-PRODUCING BACTERIUM HAVING IMPROVED PRODUCTIVITY BY GNTR DESTRUCTION 有权上生产力的提高GNTR销毁异丙基制造细菌
公开(公告)号：EP2604683A1
公开(公告)日：2013-06-19
申请号：EP11816495.3
申请日：2011-08-11
发明人： AMANO, Koh , SHIRAI, Tomokazu , TAKAHASHI, Hitoshi , HIRANO, Junichiro , MATSUMOTO, Yoshiko , TAKEBAYASHI, Nozomi , WADA, Mitsufumi , SHIMIZU, Hiroshi , FURUSAWA, Chikara , HIRASAWA, Takashi
CPC分类号： C12P7/04 , C07C1/24 , C07C45/002 , C07C2529/70 , C07K14/245 , C12N9/0006 , C12N9/88 , C12N15/70 , C12P7/28 , Y02P20/52 , C07C11/06 , C07C49/08
摘要： An isopropyl alcohol-producing Escherichia coli includes an isopropyl alcohol production system, wherein an activity of transcriptional repressor GntR is inactivated, and the isopropyl alcohol-producing Escherichia coli preferably further includes a group of auxiliary enzymes having an enzyme activity expression pattern with which isopropyl alcohol production capacity achieved by the inactivation of the GntR activity is maintained or enhanced. A method of producing isopropyl alcohol includes producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli. A method of producing acetone includes contacting the isopropyl alcohol obtained by the isopropyl alcohol production method with a complex oxide that includes zinc oxide and at least one oxide containing a Group 4 element, and that is prepared by coprecipitation. A method of producing propylene includes contacting isopropyl alcohol and acetone obtained by the production method with a solid acidic substance and a Cu-containing hydrogenation catalyst as catalysts.
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公开(公告)号：EP2546331A1
公开(公告)日：2013-01-16
申请号：EP11753297.8
申请日：2011-03-04
发明人： MATSUMOTO, Yoshiko , HIRANO, Junichiro , MORISHIGE, Takashi , SHIRAI, Tomokazu , TAKAHASHI, Hitoshi , AMANO, Koh , TAKEBAYASHI, Nozomi , WADA, Mitsufumi , SHIMIZU, Hiroshi , FURUSAWA, Chikara , HIRASAWA, Takashi
CPC分类号： C12P7/04 , C12N9/0006 , C12N9/0036 , C12N9/1029 , C12N15/70
摘要： An isopropyl alcohol-producing Escherichia coli equipped with an isopropyl alcohol production system, having at least one enhanced enzyme activity selected from the group consisting of an enhanced malate dehydrogenase, activity, an enhanced NAD(P) + transhydrogenase (AB-specific) activity, and an enhanced thiolase activity, and an isopropyl alcohol producing method including producing isopropyl alcohol from a plant-derived raw material using the isopropyl alcohol-producing Escherichia coli,
摘要翻译： 具有选自增强的苹果酸脱氢酶，活性，增强的NAD（P）+转氢酶（AB特异性）活性，增强的苹果酸脱氢酶活性，至少一种增强的酶活性的异丙醇生产系统的异丙醇生产大肠杆菌 提高的硫解酶活性，以及异丙醇生产方法，包括使用产生异丙醇的大肠杆菌从植物来源的原料生产异丙醇，
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