-
-
公开(公告)号：EP4355777A1
公开(公告)日：2024-04-24
申请号：EP22731262.6
申请日：2022-06-13
CPC分类号： C12N2510/0020130101 , C12N5/0602 , C12N2510/0220130101 , C07K16/2827 , C07K2317/3020130101 , A61P35/00
-
公开(公告)号：EP4435105A2
公开(公告)日：2024-09-25
申请号：EP24173045.6
申请日：2016-09-28
申请人： Amgen Inc.
发明人： NIOI, Paul , COWARD, Peter , MURAWSKY, Christopher , PIPER, Derek, E. , GARCES, Fernando , ZHANG, Jun , LI, Yang , CHAN, Brian, Mingtung
IPC分类号： C12N15/113
CPC分类号： C07K16/28 , C07K2317/3020130101 , C07K2317/7720130101 , A61P9/10 , A61P9/04 , C07H21/02 , A61K39/3955 , C07K2317/7620130101 , C07K2317/9220130101 , C07K2317/9420130101 , C12N15/1138 , C12N2310/1420130101
摘要： Antigen binding proteins that interact with ASGR, ASGR-1 and/or ASGR-2 are described as well as methods of making and using such antigen binding proteins. Methods of treating and preventing cardiovascular disease by administering a pharmaceutically effective amount of ASGR, ASGR-1 and/or ASGR-2 antigen binding proteins. Methods of treating and preventing cardiovascular disease by administering a pharmaceutically effective amount of interfering RNA compositions that reduce expression of ASGR, ASGR-1 and/or ASGR-2 are described.
-
公开(公告)号：EP4377330A1
公开(公告)日：2024-06-05
申请号：EP22755209.8
申请日：2022-07-27
发明人： YOUSEF, Sara , BRUNK, Fabian , MORITZ, Andreas , BUNK, Sebastian , WAGNER, Claudia , MAURER, Dominik , UNVERDORBEN, Felix
IPC分类号： C07K14/47 , A61P35/00 , C07K16/30 , A61K39/00 , C07K14/725
-
公开(公告)号：EP3356415B1
公开(公告)日：2024-05-01
申请号：EP16781931.7
申请日：2016-09-28
IPC分类号： C07K16/28 , A61K39/395 , A61P9/00 , A61P3/06 , C12N15/113
-
公开(公告)号：EP4442708A2
公开(公告)日：2024-10-09
申请号：EP24191390.4
申请日：2018-01-17
申请人： Ablynx NV
IPC分类号： C07K16/18
CPC分类号： C07K16/18 , C07K2317/2220130101 , C07K2317/3020130101 , C07K2317/3320130101 , C07K2317/56920130101 , C07K2317/9220130101 , A61P43/00
摘要： The present invention relates to amino acid sequences that can bind to serum albumin.
In particular, the present invention relates to immunoglobulin single variable domains, and in particular heavy-chain immunoglobulin single variable domains, that can bind to serum albumin.
The invention also relates to proteins, polypeptides and other constructs, compounds, molecules or chemical entities that comprise at least one of the immunoglobulin single variable domains binding to serum albumin that are described herein.-
公开(公告)号：EP4356927A3
公开(公告)日：2024-10-02
申请号：EP23214154.9
申请日：2013-10-15
申请人： Arizona Board of Regents on behalf of Arizona State University , Sierks, Michael , Tian, Huilai , Moe, James G. , Davidowitz, Eliot
CPC分类号： G01N2800/282120130101 , C07K16/005 , C07K2317/2120130101 , C07K2317/3020130101 , C07K2317/62220130101 , C07K16/18 , C12N15/1037 , G01N33/6896 , A61P25/28
摘要： The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomeric tau, fibrillar tau or nondisease associated forms of tau.
-
公开(公告)号：EP3218406B2
公开(公告)日：2024-10-02
申请号：EP15791298.1
申请日：2015-11-09
-
公开(公告)号：EP3624846B1
公开(公告)日：2024-08-07
申请号：EP17743098.0
申请日：2017-06-20
IPC分类号： A61K9/08 , A61K38/00 , A61K47/02 , A61K47/12 , A61K47/22 , C07K16/00 , C07K16/06 , C07K16/22 , C07K16/32 , A61K9/00 , A61K39/395 , A61K47/18
CPC分类号： A61K38/00 , A61K39/39591 , C07K16/00 , C07K16/06 , C07K16/22 , C07K16/241 , C07K16/2863 , C07K16/2887 , C07K16/32 , C07K2317/2420130101 , A61K9/0019 , A61K47/12 , A61K47/183 , A61K47/22 , A61K9/08 , A61K47/02 , C07K2317/2120130101 , C07K2317/3020130101 , C07K2317/3220130101 , C07K2317/5220130101 , Y02A50/30
-
公开(公告)号：EP4442707A2
公开(公告)日：2024-10-09
申请号：EP24191388.8
申请日：2018-01-17
申请人： Ablynx NV
IPC分类号： C07K16/18
CPC分类号： C07K16/18 , C07K2317/2220130101 , C07K2317/3020130101 , C07K2317/3320130101 , C07K2317/56920130101 , C07K2317/9220130101
摘要： The present invention relates to amino acid sequences that can bind to serum albumin.
In particular, the present invention relates to immunoglobulin single variable domains, and in particular heavy-chain immunoglobulin single variable domains, that can bind to serum albumin.
The invention also relates to proteins, polypeptides and other constructs, compounds, molecules or chemical entities that comprise at least one of the immunoglobulin single variable domains binding to serum albumin that are described herein.
-
-
-
-
-
-
-
-
-
搜索结果
21 条记录 (耗时 0.011 秒)
