MICROORGANISM HAVING L-TRYPTOPHAN PRODUCTIVITY AND METHOD FOR PRODUCTION OF L-TRYPTOPHAN USING SAME
    1.
    发明公开
    MICROORGANISM HAVING L-TRYPTOPHAN PRODUCTIVITY AND METHOD FOR PRODUCTION OF L-TRYPTOPHAN USING SAME 有权
    具有L-三磷酸生产力的微生物及使用相同方法生产L-三磷酸

    公开(公告)号:EP2987854A1

    公开(公告)日:2016-02-24

    申请号:EP14785937.5

    申请日:2014-04-16

    IPC分类号: C12N1/21 C12N15/54 C12P13/22

    摘要: The present invention relates to a microorganism of the genus Escherichia having enhanced L-tryptophan productivity, which has been modified to express yeast anthranilate phosphoribosyltransferase in order to be able to produce L-tryptophan at high concentration, and to a method for producing L-tryptophan, comprising a step of culturing the microorganism. The microorganism of the genus Escherichia can produce L-tryptophan, and thus can be advantageously used in the pharmaceutical industry and the feed industry, particularly for animal feed.

    摘要翻译: 本发明涉及具有增强的L-色氨酸生产力的埃希氏菌属微生物,其已被修饰以表达酵母邻氨基苯甲酸磷酸核糖基转移酶以便能够以高浓度生产L-色氨酸,并且涉及生产L-色氨酸的方法 包括培养微生物的步骤。 埃希氏菌属微生物可产生L-色氨酸,因此可有利地用于制药工业和饲料工业,特别是用于动物饲料。

    RECOMBINANT STRAIN PRODUCING O-AMINOBENZOATE AND FERMENTATIVE PRODUCTION OF ANILINE FROM RENEWABLE RESOURCES VIA 2-AMINOBENZOIC ACID
    4.
    发明公开
    RECOMBINANT STRAIN PRODUCING O-AMINOBENZOATE AND FERMENTATIVE PRODUCTION OF ANILINE FROM RENEWABLE RESOURCES VIA 2-AMINOBENZOIC ACID 审中-公开
    重组菌株合成O-氨基苯甲酸和苯胺自可再生资源的发酵生产通过2-氨基苯甲酸

    公开(公告)号:EP3108015A1

    公开(公告)日:2016-12-28

    申请号:EP15705036.0

    申请日:2015-02-19

    摘要: The invention provides a recombinant microbial host cell capable of converting a raw material comprising a fermentable carbon substrate to o-aminobenzoate biologically. The invention further provides a method for producing aniline, comprising the steps of: a) producing o-aminobenzoate by fermentation of a raw material comprising at least one fermentable carbon substrate using the recombinant microbial host cell of the capable of converting said raw material comprising at least one fermentable carbon substrate to o-aminobenzoate biologically, wherein said o-aminobenzoate comprises anthranilate anion, b) converting said o-aminobenzoate from said anthranilate anion to anthranilic acid by acid protonation, c) recovering said anthranilic acid by precipitation or by dissolving in an organic solvent, and d) converting said anthranilic acid to aniline by thermal decarboxylation in an organic solvent.

    摘要翻译: 本发明提供能够将原料包含可发酵碳底物,以邻氨基苯甲酸生物的重组微生物宿主细胞。 本发明进一步提供了用于生产苯胺,其包括以下步骤的方法:通过原料的发酵a)产生邻 - 氨基苯甲酸酯使用将所述剃刀在包括能够在重组微生物宿主细胞,其包含至少一种可发酵碳底物 至少一种可发酵碳底物,以邻氨基苯甲酸酯的生物,worin所述O氨基苯甲酸包括邻氨基苯甲酸根阴离子,b)将所述O氨基苯甲酸从所述邻氨基苯甲酸的阴离子由酸质子化,以邻氨基苯甲酸,c)中回收所述的邻氨基苯甲酸通过沉淀或通过溶解在 溶剂有机,以及d)将所述的邻氨基苯甲酸通过热脱羧在有机溶剂中的苯胺。