摘要:
Disclosed are novel microorganisms, Brevibacterium lactofermentum CJJA21 (Accession No. KCCM-10222) resistant to sodium azide and Brevibacterium lactofermentum CJJA22 (Accession No. KCCM-10223) resistant to alpha -aminobutyric acid, both of which are capable of producing L-glutamine in a higher yield than the known strains, and processes for producing L-glutamine using the same.
摘要:
The present invention provides novel microorganisms, Brevibacterium lactofermentum CJJA21 (Accession No. KCCM-10222), which is resistant to sodium azide, and Brevibacterium lactofermentum CJJA22 (Accession No. KCCM-10223), which is resistant to alpha-aminobutyric acid. These microorganisms are capable of producing L-glutamine in a higher yield than the known strains. The present invention further provides processes for producing L-glutamine using the microorganisms of the invention.
摘要:
Die Erfindung betrifft ein Verfahren zur Herstellung von L-Aminosäuren auf fermentativem Wege. Dabei kommen z. B. Mikroorganismen der Gattung Corynebacterium als Biokatalysator zur Anwendung, die bezüglich einer Aminosäure eine Auxotrophie besitzen. Das Verfahren ist dadurch gekennzeichnet, daß die Kohlenstoffquelle einerseits und die limitierende Aminosäure andererseits in zwei oder mehr verschiedenen Zufütterungsströmen dem Prozeß zugeführt werden. Dabei besitzen die Zufütterungsprofile beispielsweise eine konkave (Saccharose) und exponentielle (Aminosäure) Form oder eine konvexe (Saccharose) und ebenfalls konvexe (Aminosäure) Form, jeweils mit spezifischen unterschiedlichen Steigungsmaßen der Ströme zueinander.
摘要:
Disclosed is a method for producing folic acid, comprising incubating yeast having the ability to produce folic acid or incubating bacteria having the ability to produce folic acid of 1 mg or more per liter of the culture, thereby accumulating folic acid in the culture.
摘要:
This invention relates to a γ-cyclodextrin glucanotransferase having novel properties, to a process for the production of the γ-cyclodextrin glucanotransferase which comprises culturing a strain belonging to the genus Brevibacterium capable of producing cyclodextrin glucanotransferase, thereby allowing the strain to produce the γ-cyclodextrin glucanotransferase in a culture medium, and subsequently collecting the enzyme, to a process for the production of cyclodextrin which comprises allowing the cyclodextrin glucanotransferase to react with substrate dissolved in a solution, thereby effecting formation of γ-cyclodextrin as a main product, and to a method for increasing γ-cyclodextrin yield without accompanying yield increase of total cyclodextrin, which comprises adding ethyl alcohol to a reaction solution in which γ-cyclodextrin and β-cyclodextrin are formed from starch by the action of γ-cyclodextrin glucanotransferase, thereby effecting repressed formation of β-cyclodextrin and enhanced formation of γ-cyclodextrin. Development of the process of this invention has rendered possible low cost production of γ-cyclodextrin and therefore expands practical use of γ-cyclodextrin to the field of food and the like.