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公开(公告)号:EP4452944A1
公开(公告)日:2024-10-30
申请号:EP22850858.6
申请日:2022-12-19
发明人: CHAPMAN, Mark , DAVIES, Nicholas Gareth, Morse , GERLACH, Aaron , GRAHAM, Christopher, John , LEBRETON, Sylvain , LI, Ronghua , MA, Nina , MADDOX, Daniel , MECHIN, Ingrid , MOWREY, David , NAGARAJAN, Karthigeyan , NAIR, Anil , NORCROSS, Roger, David , REDONDO PENA, Roger Lluis , SAFAROVA, Alena , SMRCINA, Martin
IPC分类号: C07D213/57 , C07D213/61 , C07D239/34 , C07D403/04 , C07D407/04 , C07D407/12 , C07D413/04 , C07D417/04 , A61K31/44 , A61K31/513 , A61P25/00
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公开(公告)号:EP3519409B1
公开(公告)日:2024-09-18
申请号:EP17784466.9
申请日:2017-09-26
IPC分类号: C07D417/04 , C07D417/14 , C07D471/04 , C07D487/04 , A61K31/428 , A61P31/18
CPC分类号: A61P31/18 , A61K31/428 , A61K31/439 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/4985 , A61K31/519 , A61K31/5377 , A61K31/5383 , A61K31/55 , A61K31/551 , C07D417/04 , C07D417/14 , C07D471/04 , C07D471/08 , C07D487/04 , C07D487/08 , C07D487/10 , C07D491/107 , C07D498/04
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3.
公开(公告)号:EP4426680A1
公开(公告)日:2024-09-11
申请号:EP22890383.7
申请日:2022-11-02
发明人: KWON, Yong Tae , SUNG, Ki Woon , BAE, Tae Hyun , KIM, Hyun Tae , NA, Jeong Eun , KIM, Kun Young , KWON, Ha Kyoung
IPC分类号: C07D233/86 , C07D417/04 , A61K31/4166 , A61K31/496 , A61P35/00
CPC分类号: C07D233/86 , A61P35/00 , C07D417/04 , A61K45/06
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公开(公告)号:EP4408835A1
公开(公告)日:2024-08-07
申请号:EP22777727.3
申请日:2022-09-27
申请人: Zevra Denmark A/S
IPC分类号: C07D401/04 , C07D403/04 , C07D413/04 , C07D417/04 , C07D471/04 , C07D491/04 , A61P15/16 , A61K31/444
CPC分类号: C07D401/04 , C07D403/04 , C07D471/04 , C07D491/04 , C07D417/04 , C07D413/04 , A61P15/16
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5.
公开(公告)号:EP4395776A1
公开(公告)日:2024-07-10
申请号:EP22773450.6
申请日:2022-09-02
申请人: Insusense ApS
CPC分类号: A61K31/44 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/28 , C07D311/18 , C07D217/04 , C07D209/08 , C07D277/64
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公开(公告)号:EP4387957A1
公开(公告)日:2024-06-26
申请号:EP22777381.9
申请日:2022-08-18
申请人: FMC Corporation
发明人: HIE, Liana , LONG, Jeffrey Keith , AKWABOAH, Daniel , REDDY, Ravisekhara P. , SHARPE, Paula Louise , STEVENSON, Thomas Martin , WHITE, Alexander Robert
IPC分类号: C07D213/26 , C07D213/30 , C07D213/63 , C07D237/14 , C07D237/16 , C07D237/22 , C07D237/24 , C07D261/12 , C07D401/04 , C07D403/04 , C07D405/04 , C07D417/04 , A01N43/653 , A01N43/40
CPC分类号: C07D417/04 , C07D401/04 , C07D405/04 , C07D403/04 , C07D237/14 , C07D237/24 , C07D237/22 , C07D237/16 , C07D261/12 , C07D213/63 , C07D213/26 , C07D213/30
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公开(公告)号:EP4384164A1
公开(公告)日:2024-06-19
申请号:EP22856525.5
申请日:2022-08-09
IPC分类号: A61K31/404 , C07D277/20 , C07D417/04 , C07D417/14 , A61P35/00 , A61P7/06
CPC分类号: A61K31/404 , A61P7/06 , A61P35/00 , C07D417/14 , A61K31/433 , A61K31/427
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8.
公开(公告)号:EP4058448B1
公开(公告)日:2024-05-29
申请号:EP20803187.2
申请日:2020-11-12
IPC分类号: C07D417/04 , C07D233/76 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D405/04 , C07D405/14 , C07D413/04 , C07D413/14 , C07D417/14 , A61K31/427 , A61K31/4178 , A61P9/00
CPC分类号: C07D417/14 , C07D417/04 , C07D413/04 , C07D413/14 , C07D405/14 , C07D405/04 , C07D401/04 , C07D401/14 , C07D401/12 , C07D233/76 , C07D403/04 , A61P9/00
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公开(公告)号:EP4365174A1
公开(公告)日:2024-05-08
申请号:EP22833266.4
申请日:2022-06-30
发明人: TSUMURA Takeshi , ISSHIKI Satoshi , OKUE Masayuki , SASAKI Toshiro , FUSHIHARA Kenichi , MOURI Shinsuke
IPC分类号: C07D487/08 , C07D263/58 , C07D417/04
CPC分类号: C07D263/58 , C07D417/04 , C07D487/08
摘要: A method for producing a compound represented by formula (1):
or a salt thereof, comprising:
a step B of producing a compound represented by formula (3):
[in the formula (3), Boc represents a tert-butoxycarbonyl group] or a salt thereof by using a compound represented by formula (2):
[in the formula (2),
Ra represents a hydrogen atom or an optionally substituted arylmethyl group,
Rb represents an optionally substituted alkyl or cyclic alkyl group,
R3 represents a hydrogen atom, a halogen atom, or a thiazol-2-yl group, and
Xa represents a hydrogen atom or a halogen atom] or a salt thereof; and
a step C of producing the compound represented by the formula (1) or the salt thereof by using the compound represented by the formula (3) or the salt thereof.-
公开(公告)号:EP3934702B1
公开(公告)日:2024-05-08
申请号:EP20766269.3
申请日:2020-03-06
IPC分类号: A61K51/04 , A61P25/28 , C07B59/00 , C07D417/04 , G01N33/60 , C12Q1/48 , A61K101/02 , A61K101/00
CPC分类号: A61P25/28 , C07B59/002 , C07D417/04 , A61K51/0455 , G01N33/60 , C12Q1/485
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