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公开(公告)号：EP4130105A1
公开(公告)日：2023-02-08
申请号：EP22195184.1
申请日：2019-06-26
发明人： TANG, Yiqing , LEWIS, Andrew Lennard , VINCE, Jonathan , BRITTON, Hugh , ASHRAFI, Koorosh , GUÉGAN, Damien , WILLIS, Sean Leo
IPC分类号： C08J3/24 , C08L101/06 , C08K5/092 , C08F8/14 , C08F16/06 , C08J3/12 , C08J3/075 , C08L101/16 , A61K9/50 , A61K49/04 , A61K9/16 , C08K5/3445 , C08L29/04 , C07C227/18 , C07C229/62 , C08F8/30 , C08F8/48 , C07C303/32 , C07C309/11 , C07D327/04 , C08F8/34 , C08F8/12 , C08F8/26 , C08F8/02 , C07C45/71 , C07C47/575 , C07C45/63 , C07C47/565 , C07C51/363 , C07C63/10
摘要： A polymer having a backbone comprising a polyhydroxylated polymer cross linked by a C3 to C8 diacid.
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公开(公告)号：EP3239130B1
公开(公告)日：2021-10-06
申请号：EP15871593.8
申请日：2015-05-19
发明人： WANG, Nongyue , QU, Xiongwei , LI, Guohua , SHAO, Jianming , ZHAO, Quanzhong , WEN, Guoqiang
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公开(公告)号：EP3239130A1
公开(公告)日：2017-11-01
申请号：EP15871593.8
申请日：2015-05-19
发明人： WANG, Nongyue , QU, Xiongwei , LI, Guohua , SHAO, Jianming , ZHAO, Quanzhong , WEN, Guoqiang
摘要： The present invention pertains to the field of chemical technology, and relates to a clean process of preparing a chloroformyl-substituted benzene. The process of the present invention is done by oxidation of a tail gas hydrogen chloride from a chlorination reaction and a chloroacylation reaction and recycling of the resulting oxidation product chlorine gas into the chlorination reaction. The present invention provides a clean process of preparing a polymer-grade chloroformyl-substituted benzene.
摘要翻译： 本发明属于化学技术领域，涉及一种制备氯甲酰取代苯的清洁方法。 本发明的方法通过从氯化反应和氯酰化反应氧化尾气氯化氢并将所得氧化产物氯气再循环到氯化反应中来完成。 本发明提供了制备聚合物级氯甲酰基取代的苯的清洁方法。
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公开(公告)号：EP1328499B1
公开(公告)日：2010-05-05
申请号：EP01987737.2
申请日：2001-10-17
申请人： BASF CORPORATION
IPC分类号： C07C51/41 , C07C65/21 , C07C63/10 , C07C59/68 , C07C227/18
CPC分类号： C07C51/412 , C07C59/68 , C07C65/21 , C07C63/10
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5.发明公开2-SUBSTITUTED PHENYL-5,7-DIALKYL-3,7-DIHYDROPYRROLE[2,3-D]PYRIMIDINE-4-ONE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF 有权2-SUBSTITUIERTE PHENYL-5,7-DIALKYL-3,7-二氢吡咯并[2,3-D]吡啶二酮-4-ONDERIVATE，DEREN HERSTELLUNG UND PHARMAZEUCHSCHE VERWENDUNG
公开(公告)号：EP1634883A1
公开(公告)日：2006-03-15
申请号：EP04732925.5
申请日：2004-05-14
IPC分类号： C07D487/04 , C07C63/10 , C07D207/00 , C07D207/34 , A61K31/505 , A61P15/00 , C07D239/00 , C07D209/00
CPC分类号： C07D487/04 , C07C65/21
摘要： The invention relates to the compounds of formula I, their preparation and the pharmaceutical compositions containing the compounds. The invention also relates to the use of the compounds of formula I in preparing medicines, which can treat sexual dysfunction of animals including human (male and female), especially erectile dysfunction of male and the diseases in which the function of phospholipase 5 (cGMP PDE5) is involved.
摘要翻译： 本发明涉及式I化合物及其制备方法和含有该化合物的药物组合物。 本发明还涉及式I化合物在制备药物中的用途，其可以治疗包括人（男性和女性）在内的动物的性功能障碍，特别是雄性的勃起功能障碍，以及磷脂酶5（cGMP PDE5 ） 参与。
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公开(公告)号：EP1265837B1
公开(公告)日：2004-06-09
申请号：EP00977582.6
申请日：2000-11-27
发明人： GÖTZ, Roland , GÖTZ, Norbert , KEIL, Michael , WOLF, Bernd , STEINMETZ, Adrian , STAMM, Armin , HENKELMANN, Jochem
摘要： The invention relates to a method for producing o-chloromethyl benzoic acid chlorides of formula (I), in which R1 to R4 can be the same or different and represent hydrogen C¿1?-C4 alkyl, halogen or trifluoromethyl, by reacting benzo-condensed lactones of formula (II), in which R?1 to R4¿ have the above-mentioned meaning, with thionyl chloride. The inventive method is characterized in that the reaction is carried out in the presence of catalytic quantities of a Lewis acid and in the presence of catalytic quantities of a phosphine derivative.
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7.发明授权Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same 失效光学活性联苯衍生物，其制备方法，含有作为活性成分的液晶组成物以及含有它们的液晶元件。
公开(公告)号：EP0395390B1
公开(公告)日：1994-09-28
申请号：EP90304475.8
申请日：1990-04-25
发明人： Kurimoto, Tsao , Higashii, Takayuki , Toda, Shoji , Minai, Masayoshi , Sekine, Chizu , Tani, Takeshi
IPC分类号： C09K19/12 , C07C43/205 , C07C43/164 , C07C69/24 , C07C63/06 , C07C63/10
CPC分类号： C07D239/26 , C07C43/1782 , C07C43/1785 , C07C43/2055 , C07C43/23 , C07C45/59 , C07C45/673 , C07C45/676 , C07C45/71 , C07C49/215 , C07C49/82 , C07C49/83 , C07C49/84 , C07C65/105 , C07C65/24 , C07C65/40 , C07C69/007 , C07C69/017 , C07C69/734 , C07C69/76 , C07D239/34 , C09K19/126
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公开(公告)号：EP0512715A2
公开(公告)日：1992-11-11
申请号：EP92303617.2
申请日：1992-04-22
申请人： ZENECA LIMITED
IPC分类号： C07C17/12 , C07C309/86 , C07C63/10 , C07C49/327 , C07C255/50 , C07C63/70 , C07B39/00
CPC分类号： C07C303/22 , C07B39/00 , C07C17/12 , C07C45/63 , C07C255/50 , C07C49/807 , C07C309/80
摘要： Introduction of a fluoro substituent into an aromatic ring adjacent an electron donating group is difficult producing mixed isomers and low yields of desired products.
A process for the introduction of a fluoro substituent into substantially in an adjacent position to an electron-donating group into an aromatic compound in high yield is disclosed.
The fluoroaromatic compounds are useful as synthetic intermediates for example in the manufacture of agrochemicals, pharmaceuticals and dyestuffs.摘要翻译： 将氟取代基引入与供电子基团相邻的芳香环难以产生混合异构体并且所需产物的产率低。 公开了一种以高产率将氟取代基基本上与供电子基团相邻位置引入芳族化合物的方法。 氟代芳族化合物可用作例如在农药，药物和染料的制造中的合成中间体。
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公开(公告)号：EP0270964B1
公开(公告)日：1992-07-08
申请号：EP87117653.3
申请日：1987-11-28
申请人： BAYER AG
IPC分类号： C07C205/11 , C07C255/50 , C07C201/16 , C07C51/64 , C07C63/10
CPC分类号： C07C17/38 , C07C45/80 , C07C51/64 , C07C63/70 , C07C201/12 , C07C201/16 , C07C253/34 , C07C317/00 , C07C205/12 , C07C205/58
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10.发明授权Nouveau procédé de préparation de chlorures d'acides par phosgénation des acides et catalyseurs pour ce procédé 失效通过羧酸的磷酸化制备羧酸氯化物的方法和本方法的催化剂
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