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公开(公告)号：EP3577598A1
公开(公告)日：2019-12-11
申请号：EP18702191.0
申请日：2018-01-24
申请人： Elekta AB (publ)
发明人： HILLBORG, Mikael
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公开(公告)号：EP3417787A1
公开(公告)日：2018-12-26
申请号：EP17177068.8
申请日：2017-06-21
申请人： Elekta AB (PUBL)
发明人： ADLER, Jonas
摘要： Much of the image processing that is applied to medical images is a form of "inverse problem". This is a class of mathematical problems in which a "forward" model by which a signal is converted into dataset is known, to at least some degree, but where the aim is to reconstruct the signal given the resulting dataset. Thus, an inverse problem is essentially seeking to discover x given knowledge of A(x)+noise by finding an appropriate reconstruction operator A † such that A † (A(x)+noise) ≈ x, thereby enabling us to obtain x (or a close approximation) given knowledge of an output dataset consisting of A(x)+noise. Generally, several such processes (or their equivalents) are applied to the image dataset. If the first process (for example, noise reduction) is expressed via a first reconstruction operator A 1 † characterised by a parameter set Θ 1 , and the second process (for example, segmentation) is expressed via a second reconstruction operator A 2 † characterised by a parameter set Θ 2 , then the result of the two steps applied consecutively is A 2 † ( A 1 † ( y )). This can be expressed as an overall reconstruction operator F † , characterised by a parameter set Φ. If we then allow a machine learning process to optimise F † , then the steps previously carried out separately can be combined into a single optimisation. This yields advantages in terms of computational load and in the accuracy of the end result.
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94.发明授权
公开(公告)号：EP1880226B1
公开(公告)日：2018-11-28
申请号：EP06725888.9
申请日：2006-04-21
申请人： Elekta AB (publ.)
IPC分类号： G01R33/025 , A61B5/04 , G06F17/00
CPC分类号： A61B5/04008 , G01R33/025
摘要： The present invention recognises and eliminates from a biomagnetic measurement signal interferences whose source is disposed in the direct vicinity of an object being measured. The invention utilises the SSS method that can be used to separate from one another the signals associated with the internal and external sources of a set of measurement sensors by calculating two series developments. The sources to be examined in the invention and disposed in the so-called intermediate space produce a component to both of the developments, and can, therefore, be detected by means of an analysis to be performed in a time domain. This division into components can be made using the Principal Component Analysis (PCA), the Independent Component Analysis (ICA) or the Singular Value Decomposition. Finally, the clarified interferences in the intermediate space can be eliminated from the measured signal using, for example, the linear algebraic orthogonal projection.
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公开(公告)号：EP3142747B1
公开(公告)日：2018-09-19
申请号：EP15728421.7
申请日：2015-05-13
申请人： Elekta AB (PUBL)
CPC分类号： A61N5/1045 , A61N2005/1089 , A61N2005/1095 , G21K1/025 , G21K1/046
摘要： Embodiments disclose a radiotherapy apparatus comprising a source of radiation configured to emit a beam of radiation and a collimator structure configured to limit a lateral extent of the beam, the collimator structure including a primary collimator configured to shape the beam, a first collimator comprising a plurality of adjacent elongate leaves, the leaves being extendable into the beam in a first direction transverse to the beam, and a block collimator including an aperture configured to permit the beam to pass through, the block collimator being extendable into the beam in a second direction transverse to the beam and transverse to the first direction. In some embodiments, the aperture may be cone-shaped or a through-hole, which may be empty or filled with a radiotransparent material. In some embodiments, the block collimator may include a plurality of apertures, which may be of varying dimensions.
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公开(公告)号：EP2995347B1
公开(公告)日：2018-03-21
申请号：EP15183347.2
申请日：2015-09-01
申请人： Elekta AB (publ)
发明人： Allen, John , Winfield, Colin
CPC分类号： A61N5/1049 , A61B6/032 , A61N5/1036 , A61N5/1047 , A61N5/107 , A61N5/1081 , A61N5/1083 , A61N2005/1054 , A61N2005/1074
摘要： A radiotherapy apparatus comprises a source for producing a beam of ionising radiation along an axis, the beam covering a maximum aperture of the source, a collimator for collimating the beam to produce a collimated beam covering a sub-part of the maximum aperture, a patient support positioned in the path of the beam, a rotatable gantry, on which the source is mounted, for rotating the source around the patient support thereby to deliver the beam from a range of directions, an imaging device located opposite the source and with the patient support between the source and the imaging device, and mounted on the gantry via a drive member allowing translational motion of the imaging device in at least one direction perpendicular to the axis, and a control unit adapted to control the drive member to move the imaging device within the maximum aperture and maintain coincidence between the imaging device and the sub-part of the maximum aperture. Accordingly, the EPID can be moved during the treatment in order to maintain the collimated field of the radiation beam within the bounds of the EPID. This ensures that the image is valid and prevents damage to the EPID as a result of exposure of more sensitive (or less shielded) parts to the beam.
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公开(公告)号：EP2111798B1
公开(公告)日：2017-06-07
申请号：EP08154930.5
申请日：2008-04-22
申请人： Elekta AB (publ)
发明人： Markström, Mårten
IPC分类号： A61B6/04
CPC分类号： A61B6/04 , A61B6/0421 , A61N5/1084 , A61N2005/1097
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公开(公告)号：EP3160584A1
公开(公告)日：2017-05-03
申请号：EP15729790.4
申请日：2015-06-10
申请人： Elekta AB (PUBL)
发明人： BROWN, Kevin
IPC分类号： A61N5/10 , A61B5/055 , A61B5/113 , G01R33/567 , A61M16/00
CPC分类号： A61B5/055 , A61B5/113 , A61B5/4887 , A61B5/7292 , A61M16/021 , A61M16/06 , A61M16/202 , A61M2205/33 , A61N5/1068 , A61N2005/1055 , G01R33/28 , G01R33/4812 , G01R33/56509 , G01R33/5676
摘要： The valve of an active breathing control (ABC) device can be driven by the output of the navigator channel of the MRI scanner, rather than by inference from a measured breath flow rate. Where the MRI scanner is integrated with a radiotherapy device, the MRI data can be used to trigger the enforced breath-hold by the ABC, and the radiotherapy delivered while the ABC valve is shut. If the MRI data pertains to the actual position of the tumour, then the ABC device will (in effect) hold the tumour at a precise and reproducible point for treatment.
摘要翻译： 用于使患者成像的设备包括磁共振成像仪（MRI），具有适于防止呼吸在至少一个方向上流动的可选择性关闭阀的呼吸控制装置（例如主动呼吸控制装置或ABC装置或面罩），以及 控制装置，其适于（i）利用MRI装置获得患者的扫描以产生1D / 2D输出图像，（ii）分析所述输出图像，以及（iii）关闭阀以防止呼吸，如果图像 符合确定的标准。 在另一个实施例中，该设备可以与放射治疗装置组合以将治疗辐射传送给用户。 在该实施例中，控制装置用于在阀关闭时触发辐射的输送。
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公开(公告)号：EP3142747A1
公开(公告)日：2017-03-22
申请号：EP15728421.7
申请日：2015-05-13
申请人： Elekta AB (PUBL)
CPC分类号： A61N5/1045 , A61N2005/1089 , A61N2005/1095 , G21K1/025 , G21K1/046
摘要： Embodiments disclose a radiotherapy apparatus comprising a source of radiation configured to emit a beam of radiation and a collimator structure configured to limit a lateral extent of the beam, the collimator structure including a primary collimator configured to shape the beam, a first collimator comprising a plurality of adjacent elongate leaves, the leaves being extendable into the beam in a first direction transverse to the beam, and a block collimator including an aperture configured to permit the beam to pass through, the block collimator being extendable into the beam in a second direction transverse to the beam and transverse to the first direction. In some embodiments, the aperture may be cone-shaped or a through-hole, which may be empty or filled with a radiotransparent material. In some embodiments, the block collimator may include a plurality of apertures, which may be of varying dimensions.
摘要翻译： 实施例公开了一种放射治疗装置，其包括被配置为发射辐射束的辐射源和被配置为限制束的横向范围的准直器结构，所述准直器结构包括被配置成使束成形的主准直器;准直器，包括多个 相邻细长叶片的叶片可沿横向于束的第一方向延伸到束中，并且块准直器包括构造成允许束通过的孔，块准直器可沿第二方向横向延伸到束中 并且横向于第一方向。 在一些实施例中，孔可以是圆锥形的或通孔，其可以是空的或用无线电透射材料填充。 在一些实施例中，块准直器可以包括可以具有不同尺寸的多个孔。
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公开(公告)号：EP3126001A1
公开(公告)日：2017-02-08
申请号：EP15713908.0
申请日：2015-04-07
申请人： Elekta AB (PUBL)
IPC分类号： A61N5/10
CPC分类号： A61N5/1067 , A61N5/1031 , A61N5/1037 , A61N5/1038 , A61N5/1039 , A61N5/1047 , A61N5/1049 , A61N5/1071 , A61N2005/1034 , A61N2005/1054 , A61N2005/1055 , A61N2005/1058
摘要： The disclosed systems and methods for Image-Guided Radiation Therapy (IGRT), utilises an iterative approach which adjusts a treatment plan based on inter- or intra-fraction images to improve the accuracy of the radiation delivered during the overall treatment. The prescribed dose of radiotherapeutic radiation is mapped onto the patient's anatomy using an image acquired of the region, which is to be the target for radiotherapeutic radiation. Following beam-angle-optimisation, fluence optimisation and segmentation, the efficiency of delivery of each segment is determined using an objective function, and the segments ranked according to their efficiency. The plan proceeds with the choice of the most efficient segment (or segments) to be delivered first. When this radiation has been delivered, having been tracked to establish its distribution, this delivered distribution can be subtracted from the original prescribed dose and the process repeated so that the delivered radiation gradually converges on the original prescribed dose.
摘要翻译： 所公开的图像引导辐射治疗系统和方法（IGRT）采用迭代方法，该方法基于图像间或图像内图像调整治疗计划，以提高整个治疗期间传递的辐射的准确度。 将放射治疗辐射的规定剂量映射到患者的解剖结构上，使用获得的该区域的图像，该区域将成为放射治疗辐射的靶标。 在光束角优化，能量密度优化和分割之后，使用目标函数确定每个片段的传递效率，并根据片段的效率进行分级。 该计划继续选择首先要交付的最有效的细分（或细分）。 当这种辐射已经被传送时，已被跟踪以建立其分布，可以从原始规定的剂量中减去该传送的分布，并重复该过程，使得递送的辐射逐渐收敛于原始的规定剂量。
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