公开(公告)号：EP1608365A1

公开(公告)日：2005-12-28

申请号：EP04724735.8

申请日：2004-03-31

申请人： Sucampo AG ,  Astellas Pharma Inc.

发明人： UENO, Ryuji ,  NAGASHIMA, A.,c/o Fujisawa Pharmaceutical Co.,Ltd ,  INOUE, T.,c/o Fujisawa Pharmaceutical Co., Ltd. ,  OHKUBO, M.,c/o Fujisawa Pharmaceutical Co., Ltd. ,  YOSHIHARA, K.,c/o Fujisawa Pharmaceutical Co. Ltd

IPC分类号： A61K31/426 ,  A61P27/00 ,  A61P17/00 ,  A61P11/00

CPC分类号： A61K31/4162 ,  A61K31/426

摘要： The present invention provides a method for treating a vascular hyperpermeable disease (except macular edema), which method comprises administering to a patient in need thereof a vascular adhesion protein-1 (VAP-1) inhibitor in an amount sufficient to treat said patient for said disease. The agents are 2-acylamino thiazole compounds.

公开(公告)号：EP1142576B1

公开(公告)日：2005-03-02

申请号：EP98961549.7

申请日：1998-12-25

申请人： Sucampo AG

发明人： Ueno, Ryuji

IPC分类号： A61K31/557 ,  A61P27/06

CPC分类号： A61K31/557 ,  A61K2300/00

摘要： Simultaneously using both a non-FP receptor agonist type prostaglandin compound (such as isopropyl unoprostone) and an FP receptor agonist type prostaglandin compound (such as latanoprost) brings about a synergistically enhanced ocular tension lowering effect.

公开(公告)号：EP1406700A1

公开(公告)日：2004-04-14

申请号：EP02741390.5

申请日：2002-07-02

申请人： Sucampo AG

发明人： UENO, Ryuji

IPC分类号： A61P37/06 ,  A61P17/00 ,  A61K31/435 ,  A61K31/495 ,  A61K31/535 ,  A61K38/13

CPC分类号： A61K45/06 ,  A61K31/436 ,  A61K31/496 ,  A61K31/535 ,  A61K38/13 ,  A61K2300/00

摘要： The present invention provides a composition for topical administration comprising an interleukin 2 inhibitor and an antimicrobial agent as active ingredients thereof, wherein said interleukin 2 inhibitor contains a tricyclo compound as shown by the general formula (I) or pharmaceutically acceptable salt thereof. The present invention further provides a method for treating inflammations and/or infections comprising topical administration of an effective amount of an interleukin 2 inhibitor and an antimicrobial agent to a subject in need of the treatment of inflammations and/or infections.

公开(公告)号：EP1389116A1

公开(公告)日：2004-02-18

申请号：EP02771715.6

申请日：2002-05-17

申请人： Sucampo AG

发明人： UENO, Ryuji

IPC分类号： A61K31/557 ,  C07C405/00

CPC分类号： A61K31/5575 ,  C07C405/00

摘要： The present invention relates to a novel cathartic composition that is useful for relieving or preventing constipation, and also for cleansing the gastrointestinal tract. The composition comprises a cathartic-inducing effective amount of halogenated bioactive lipid comprising the following partial structure (I)

公开(公告)号：EP1280523A2

公开(公告)日：2003-02-05

申请号：EP01925949.8

申请日：2001-04-26

申请人： Sucampo AG ,  FUJISAWA PHARMACEUTICAL CO., LTD.

发明人： UENO, Ryuji

IPC分类号： A61K31/167

CPC分类号： A61K31/551 ,  A61K31/165 ,  A61K31/495

摘要： This invention relates to an ocular tension depressor containing a specific benzamide derivative as an active ingredient.

公开(公告)号：EP1272194A2

公开(公告)日：2003-01-08

申请号：EP01912374.4

申请日：2001-03-15

申请人： Sucampo AG

发明人： UENO, Ryuji

IPC分类号： A61K31/557 ,  A61K31/5575 ,  A61P27/06

CPC分类号： A61K31/5585 ,  A61K31/557 ,  A61K31/5575

摘要： Disclosed is treatment of ocular hypertension and glaucoma by long-term therapy with a prostaglandin related compound for eliminating or reducing potential iridic pigmentation. Composition useful for the treatment, and use of the prostaglandin related compound for producing the composition are also disclosed.

公开(公告)号：EP3035925A4

公开(公告)日：2017-03-29

申请号：EP14838126

申请日：2014-08-21

申请人： SUCAMPO AG

发明人： UENO RYUJI

IPC分类号： A61K31/19 ,  A61P25/02 ,  A61P25/04

CPC分类号： C07C57/26 ,  A61K31/352 ,  C07C53/134

摘要： A method for treating neuropathic pain in a mammalian subject, which comprises administering an effective amount of a fatty acid derivative, is provided.

摘要翻译： 提供一种治疗哺乳动物受试者神经性疼痛的方法，其包括施用有效量的脂肪酸衍生物。

公开(公告)号：EP1791545B1

公开(公告)日：2016-08-31

申请号：EP05782157.1

申请日：2005-09-01

申请人： Sucampo AG

发明人： UENO, Ryuji

IPC分类号： A61K31/557 ,  A61K31/558 ,  A61P1/04 ,  A61P1/08 ,  A61P1/14

CPC分类号： C07D311/94 ,  A61K31/557 ,  A61K31/558

公开(公告)号：EP1861169B1

公开(公告)日：2016-05-11

申请号：EP06730328.9

申请日：2006-03-22

申请人： Sucampo AG ,  NORTH CAROLINA STATE UNIVERSITY

发明人： UENO, Ryuji ,  KUNO, Sachiko ,  BLIKSLAGER, Anthony, T. ,  MOESER, Adam, J.

IPC分类号： A61P1/04 ,  A61P35/00 ,  A61K31/557 ,  C07C405/00

CPC分类号： C07C405/00 ,  A61K31/557

公开(公告)号：EP3008171A1

公开(公告)日：2016-04-20

申请号：EP14810771.7

申请日：2014-06-12

申请人： Sucampo AG

发明人： UENO, Ryuji ,  KUNO, Sachiko ,  CUPPOLETTI, John

IPC分类号： C12N5/0735

CPC分类号： C07D311/94 ,  A61K31/352 ,  A61K31/5575

摘要： A method for suppressing tumorigenicity of stem cells in a mammalian subject, which comprises administering an effective amount of a fatty acid derivative and a method for suppressing tumorigenicity of stem cells of a mammalian subject, which comprises contacting said stem cell with an effective amount of a fatty acid derivative, are provided.